1857-57-4Relevant articles and documents
Synthesis and evaluation of macrocyclic diarylether heptanoid natural products and their analogs
Bryant, Vashti C.,Kishore Kumar,Nyong, Abijah M.,Natarajan, Amarnath
, p. 245 - 248 (2012/03/10)
The macrocyclic diarylether heptanoid (MDEH) natural products have been used in folk medicine for centuries. MDEHs are reported to exert anti-tumor properties by inhibiting the activation of NF-κB. Here we report the synthesis of a small MDEH library (first reported synthesis of racemic platycarynol) using a Grubbs cross metathesis/Ullmann cyclization strategy. Evaluation of the library led to the identification of MDEH 9b which sensitizes pancreatic cancer cells to gemcitabine mediated growth inhibition and apoptosis.
INDENONCARBOXYLIC ACIDS DERIVATIVES AND THEIR USE FOR THE TREATMENT OF AND PREVENTING DIABETES AND DYSLIPIDAEMIA
-
Page 67-68, (2008/06/13)
The present invention relates to a compound of the formula ((I): in which: n is an integer chosen from 1, 2 and 3; Y represents O; N-OR9, in which R9represents H or a saturated hydrocarbon-based aliphatic group; CR10R
Synthesis of α-keto esters and amides via oxidative cleavage of cyanoketophosphoranes by dimethyldioxirane
Wong,Yu,Yuen,Yang
, p. 3606 - 3609 (2007/10/03)
-