185757-76-0

Upstream product

• 185757-69-1 Benzoic acid (Z)-(1R,3S,4S)-3,8-bis-benzyloxy-6-benzyloxymethyl-1-methyl-5-methylene-2-oxo-4-triethylsilanyloxy-oct-6-enyl ester 
• 185757-68-0 Benzoic acid (Z)-(1R,3S,4S)-3,8-bis-benzyloxy-6-benzyloxymethyl-4-hydroxy-1-methyl-5-methylene-2-oxo-oct-6-enyl ester 
• 185757-72-6 (Z)-(4S,5S)-4,9-Bis-benzyloxy-7-benzyloxymethyl-6-methylene-5-triethylsilanyloxy-non-7-en-3-one 
• 185757-70-4 (Z)-(2R,4R,5S)-4,9-Bis-benzyloxy-7-benzyloxymethyl-6-methylene-5-triethylsilanyloxy-non-7-ene-2,3-diol 
• 185757-71-5 (Z)-(2S,3S)-2,7-Bis-benzyloxy-5-benzyloxymethyl-4-methylene-3-triethylsilanyloxy-hept-5-enal 
• 185757-74-8 (4S,5S,7S,8R)-4,9-Bis-benzyloxy-7-benzyloxymethyl-5,7,8-trihydroxy-6-methylene-nonan-3-one 
• 185757-73-7 (Z)-(4S,5S)-4,9-Bis-benzyloxy-7-benzyloxymethyl-5-hydroxy-6-methylene-non-7-en-3-one 
• 100-39-0 benzyl bromide 
• 93877-21-5 1,4-dibenzyloxybut-2-yne 
• 68972-96-3 (Z)-1,4-dibenzyloxy-2-butene 
• 185757-75-9 (1R,2S)-2-Benzyloxy-1-[(S)-2-((1S,2R)-3-benzyloxy-1-benzyloxymethyl-1,2-dihydroxy-propyl)-oxiranyl]-1-hydroxy-pentan-3-one 

Relevant academic research and scientific papers

Studies towards the synthesis of the zaragozic acids: A novel epoxide cyclisation approach to the formation of the bicyclic acetal core

Model studies towards the bicyclic acetal core 1 of the zaragozic acids, based on the epoxide cyclisation reaction 4 → 3, are described. Epoxide 14 provides the desired bicyclic acetal skeleton 16, while epoxide 27 leads through 28 to an isomeric acetal 30.