185761-23-3

Basic information

• Product Name: (R)-2-Phenyl-3-((R)-4-phenyl-4,5-dihydro-oxazol-2-yl)-propionitrile
• Synonyms: (R)-2-Phenyl-3-((R)-4-phenyl-4,5-dihydro-oxazol-2-yl)-propionitrile
• CAS NO: 185761-23-3
• Molecular Weight: 276.338
• Mol File: 185761-23-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-2-Phenyl-3-((R)-4-phenyl-4,5-dihydro-oxazol-2-yl)-propionitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-Phenyl-3-((R)-4-phenyl-4,5-dihydro-oxazol-2-yl)-propionitrile(185761-23-3)
• EPA Substance Registry System: (R)-2-Phenyl-3-((R)-4-phenyl-4,5-dihydro-oxazol-2-yl)-propionitrile(185761-23-3)

Safety Data

• Hazardous Substances Data: 185761-23-3(Hazardous Substances Data)

Upstream product

• 5804-85-3 diethylaluminium cyanide 
• 174907-60-9 (4R)-4-phenyl-2-<(E)-2-phenylethenyl>-4,5-dihydrooxazole 

Downstream Products

• 185761-26-6 (R)-2-Phenyl-2-((R)-4-phenyl-4,5-dihydro-3H-pyrrol-2-ylamino)-ethanol 
• 1078-21-3 (R)-Phenibut 

Relevant articles and documents

Enantioselective syntheses of (R)-3-phenyl GABA, (R)-baclofen and 4-arylpyrrolidin-2-ones

Enantioselective synthesis of (R)-4-amino-3-phenylbutyric acid and (R)-baclofen has been achieved through a diastereoselective conjugate addition of cyanide to enantiomerically pure 2-(2-arylethenyl)oxazolines, followed by chemoselective reduction into cyclic amidines.