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1858-47-5

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1858-47-5 Usage

General Description

Ethylamphetamine hydrochloride is a compound that contains an ethyl group attached to the amphetamine molecule and forms a salt with hydrochloric acid. The chemical is a central nervous system stimulant with similar effects to amphetamine, such as increased alertness, focus, and wakefulness. It has potential for abuse and is regulated in many countries as a controlled substance. Ethylamphetamine hydrochloride has been studied for its potential therapeutic applications in conditions such as narcolepsy and attention-deficit hyperactivity disorder, but due to its potential for abuse and negative side effects, it is not widely used in medical practice.

Check Digit Verification of cas no

The CAS Registry Mumber 1858-47-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,8,5 and 8 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1858-47:
(6*1)+(5*8)+(4*5)+(3*8)+(2*4)+(1*7)=105
105 % 10 = 5
So 1858-47-5 is a valid CAS Registry Number.

1858-47-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name Phenethylamine, N-ethyl-.α.-methyl-, hydrochloride

1.2 Other means of identification

Product number -
Other names Ethylamphetamine hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1858-47-5 SDS

1858-47-5Downstream Products

1858-47-5Relevant articles and documents

Involvement of CYP2D6 in the in vitro metabolism of amphetamine, two N-alkylamphetamines and their 4-methoxylated derivatives

Bach, Mimi V.,Coutts,Baker

, p. 719 - 732 (1999)

1. Amphetamine (AM) and five amphetamine derivatives, N-ethylamphetamine (NEA), N-butylamphetamine (NBA), 4-methoxyamphetamine (M-AM), 4-methoxy-N-ethylamphetamine (M-NEA) and 4-methoxy-N-butylamphetamine (M-NBA) were incubated with microsomal preparations from cells expressing human CYP2D6 to determine whether the enzyme was capable of catalyzing the direct ring oxidation of all substrates; the N-dealkylation of NEA, NBA, M-NEA and M-NBA; and the O-demethylation of M-AM, M-NEA and M-NBA. 2. None of the six compounds examined was N-dealkylated to any extent. 3. The only metabolites produced from AM, NEA and NBA were the corresponding ring 4-hydroxylated compounds, and the rates of formation were low. 4. All ring 4-methoxylated substrates were efficiently O-demethylated by CYP2D6 to their corresponding phenols. The size of the N-alkyl group influenced the rates of formation of these phenolamines. In contrast to reported findings with 2- and 3-methoxyamphetamines, none of the 4-methoxyamphetamines was ring-oxidized in the CYP2D6 enzyme system to 2- or 3-hydroxy-4-methoxyamphetamines or to dihydroxy-amphetamines.

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