185815-56-9

Basic information

• Product Name: 2,4-Dicyano-3-(2-Methylpropyl)-pentanediaMide
• Synonyms: 2,4-Dicyano-3-(2-Methylpropyl)-pentanediaMide;Pregabalin Impurity 9
• CAS NO: 185815-56-9
• Molecular Formula: C11H16N4O2
• Molecular Weight: 236.27034
• Product Categories: Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 185815-56-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 551.0±50.0 °C(Predicted)
• Appearance: /
• Density: 1.181±0.06 g/cm3(Predicted)
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 18.20±0.50(Predicted)
• Stability: Hygrscopic
• CAS DataBase Reference: 2,4-Dicyano-3-(2-Methylpropyl)-pentanediaMide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Dicyano-3-(2-Methylpropyl)-pentanediaMide(185815-56-9)
• EPA Substance Registry System: 2,4-Dicyano-3-(2-Methylpropyl)-pentanediaMide(185815-56-9)

Safety Data

• Hazardous Substances Data: 185815-56-9(Hazardous Substances Data)

Usage

Uses

2,4-Dicyano-3-(2-methylpropyl)-pentanediamide is an impurity of Pregabalin (P704800), a GABA (A602920) analogue used as an anticonvulsant.

Upstream product

• 590-86-3 isovaleraldehyde 
• 107-91-5 cyanoacetic acid amide 

Downstream Products

• 181289-25-8 (3S)-3-(2-methoxy-2-oxoethyl)-5-methylhexanoic acid 
• 143420-53-5 (E)-2-cyano-5-methylhex-2-enamide 

Relevant articles and documents

Preparation method and application of high-purity dimethyl 3-isobutylglutarate

The invention provides a preparation method and application of high-purity dimethyl 3-isobutylglutarate. Specifically, the invention provides the method for preparing dimethyl 3-isobutylglutarate shown as a formula 2, and the method comprises the step of enabling 3-isobutylglutaric acid to react in methanol in the presence of potassium permanganate and concentrated sulfuric acid, so as to obtain the high-purity dimethyl 3-isobutylglutarate. The method is simple, easy to control, high in product conversion rate, mild in reaction condition, convenient for industrial production and low in cost, the product is easy to purify, and the purity is up to 99% or above.