185816-33-5Relevant articles and documents
A short, convergent synthesis of two chiral antiviral agents, (+) carbocyclic 2′-deoxy-5-[(E)-2-bromovinyl] uridine and (+) carbocyclic 2′-deoxyguanosine
Borthwick, Alan D.,Crame, Andrew J.,Exall, Anne M.,Weingarten, Gordon G.,Mahmoudian, Mahmuod
, p. 6929 - 6932 (2007/10/02)
Stereo selective microbial reduction of ketone 2 gave the alcohol 5 which was coupled under Mitsunobu conditions with the protected pyrimidine 7 and purine 10 to give on deprotection the chiral antiviral nucleosides (+) carbocyclic 2′-deoxy-5-[(E)-2bromov