185855-11-2Relevant academic research and scientific papers
Stereoselective Synthesis of P-Stereogenic N-Phosphinyl Compounds
Chelouan, Ahmed,Recio, Roco,lvarez, Eleuterio,Khiar, Noureddine,Fernndez, Inmaculada
, p. 255 - 259 (2016/02/14)
A number of P-stereogenic N-phosphinyl compounds were stereoselectively prepared in good yields by a straightforward approach, thanks to the diversified and, up until now, unexplored reactivity of (R)- and (S)-dicyclohexylidene-D-glucose methyl phenyl pho
Practical synthesis of chiral vinylphosphine oxides by direct nucleophilic substitution. Stereodivergent synthesis of aminophosphine ligands
Oliana, Marco,King, Frank,Horton, Peter N.,Hursthouse,Hii, King Kuok
, p. 2472 - 2479 (2007/10/03)
A practical synthesis of optically pure alkylphenylvinylphosphine oxides is described, utilizing a nucleophilic displacement at phosphorus to install the vinyl moiety. The products were used to prepare classes of P-stereogenic aminophosphine (PN) and aminohydroxyphosphine (PNO) ligands. Stereocontrol can be exerted at various stages of the synthesis, to provide specific combinations of chirality in the final product. The effect of the stereogenic phosphorus and match-mismatch of chiralities of PNO ligands were examined in the asymmetric ruthenium-catalyzed hydrogen transfer reduction of three aryl ketones.
A generalization of the base effect on the diastereoselective synthesis of sulfinic and phosphinic esters
Fernandez, Inmaculada,Khiar, Noureddine,Roca, Aranzazu,Benabra, Abdelhak,Alcudia, Ana,Espartero, Jose L.,Alcudia, Felipe
, p. 2029 - 2032 (2007/10/03)
Various chiral secondary alcohols have been used to study the dependence of the stereochemical outcome of sulfinate and phosphinate ester synthesis on the nature of the base used to catalyse the reaction. From this study it has been shown that the achiral
