2240-41-7

Basic information

• Product Name: PHENYLPHOSPHONIC ACID DIMETHYL ESTER
• Synonyms: PHENYLPHOSPHONIC ACID DIMETHYL ESTER;o,o-dimethylphenylphosphonate;Phosphonic acid, phenyl-, dimethyl ester;Phosphonicacid,phenyl-,dimethylester;phosphonicacid,phenyl-,o,o-dimethylester;BENZENEPHOSPHONIC ACID DIMETHYL ESTER;DIMETHYL BENZENEPHOSPHONATE;DIMETHYL PHENYLPHOSPHONATE
• CAS NO: 2240-41-7
• Molecular Formula: C₈H₁₁O₃P
• Molecular Weight: 186.14
• Mol File: 2240-41-7.mol
• Article Data: 68

Chemical Properties

• Boiling Point: 247 °C
• Flash Point: 154 °C
• Appearance: /
• Density: 1.19
• Refractive Index: 1.5080 to 1.5100
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: PHENYLPHOSPHONIC ACID DIMETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: PHENYLPHOSPHONIC ACID DIMETHYL ESTER(2240-41-7)
• EPA Substance Registry System: PHENYLPHOSPHONIC ACID DIMETHYL ESTER(2240-41-7)

Safety Data

• RTECS: TA0378000
• Hazardous Substances Data: 2240-41-7(Hazardous Substances Data)

Usage

General Description

Phenylphosphonic acid dimethyl ester, also known as dimethyl phenylphosphonate, is a colorless, oily liquid that is commonly used as a chemical intermediate in the production of various organic compounds. It is widely used in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals. Phenylphosphonic acid dimethyl ester is also used as a flame retardant in plastics and as a coupling agent in the production of polymers. Additionally, it has applications in the manufacture of insecticides and as a component in the production of complexing agents for metal ions. Overall, phenylphosphonic acid dimethyl ester plays a crucial role in various industries due to its diverse chemical properties and applications.

InChI:InChI=1/C8H11O3P/c1-6-4-3-5-7(2)8(6)12(9,10)11/h3-5H,1-2H3,(H2,9,10,11)/p-2

Upstream product

• 824-72-6 P,P-dichlorophenylphosphine oxide 
• 67-56-1 methanol 
• 71-43-2 benzene 
• 17674-28-1 dimethyl acetylphosphonate 
• 186581-53-3 diazomethane 
• 10088-45-6 methyl phenylphosphonic acid 
• 124-41-4 sodium methylate 
• 868-85-9 Dimethyl phosphite 
• 78-92-2 iso-butanol 
• 108-93-0 cyclohexanol 
• 2946-61-4 phenylphosphonous acid dimethyl ester 
• 33972-66-6 3-methyl-1-nitro-but-1-ene 
• 74-88-4 methyl iodide 
• 167955-25-1 Methyl phenylpyrophosphonate 

Downstream Products

• 10088-45-6 methyl phenylphosphonic acid 
• 142671-06-5 C₄₄H₄₁O₉P₃Si₂ 
• 824-72-6 P,P-dichlorophenylphosphine oxide 
• 5761-97-7 methyl(phenyl)phosphinic chloride 
• 54835-97-1 (S)-P-methyl-P-phenylphosphinic amide 
• 185855-09-8 (S)-1,2:5,6-di-O-cyclohexylidene-D-glucose methyl phenyl phosphinate 
• 185855-11-2 (R)-1,2:5,6-di-O-cyclohexylidene-D-glucose methyl phenyl phosphinate 
• 1208347-16-3 (S)-N-(benzylidene) methyl phenylphosphinamide 

Relevant articles and documents

Synthesis of Dimethyl Phenylphosphonates Catalyzed by Group VI Metal(0) Hexacarbonyls

The coupling of dimethyl phosphite and iodobenzene occurs in the presence of catalytic amounts of homoligand carbonyl complexes of chromium subgroup metals to form dimethyl phenylphosphonate in yields of 50–73% depending on the metal.

C-P bond formation of cyclophanyl-, and aryl halides: Via a UV-induced photo Arbuzov reaction: A versatile portal to phosphonate-grafted scaffolds

A new versatile method for the C-P bond formation of (hetero)aryl halides with trimethyl phosphite via a UV-induced photo-Arbuzov reaction, accessing diverse phosphonate-grafted arenes, heteroarenes and co-facially stacked cyclophanes under mild reaction

Photoinduced transition-metal and external photosensitizer free cross-coupling of aryl triflates with trialkyl phosphites

Photoinduced phosphonation of aryl triflates with trialkyl phosphites via a tandem single-electron-transfer, C-O bond cleavage and Arbuzov rearrangement process in the absence of transition-metal and external photosensitizer is reported herein. The protoc

Cobalt catalyzed C-P bond formation by cross-coupling of boronic acids with P(O)H compounds in presence of zinc

In our current work, we have reported the first cobalt-catalyzed cross-coupling of arylboronic acid with alkyl/aryl phosphites under mild conditions. The reaction was carried out in the presence of zinc powder as an additive and ter-pyridine as a ligand. The use of non-precious cobalt salt makes the protocol advantageous, as it is inexpensive and more abundant than the previously used methods where precious metal salts (Pd and Pt) were used. The reaction has a wide substrate scope and the products were obtained in good yields.