185903-57-5Relevant articles and documents
Tandem Enyne Allene-Radical Cyclization: Low-Temperature Approaches to Benz[e]indene and Indene Compounds
Grissom, Janet Wisniewski,Klingberg, Detlef,Huang, Dahai,Slattery, Brian J.
, p. 603 - 626 (2007/10/03)
In an effort to lower the temperatures required to prepare multicyclic compounds using the tandem enediyne-radical cyclization, we have developed the tandem enyne allene-radical cyclization which proceeds at temperatures as low as 37°C. The reactions were
Tandem enyne allene-radical cyclization via base-catalyzed isomerization of enediyne sulfones
Grissom,Wisniewski, Janet,Klingberg
, p. 6607 - 6610 (2007/10/02)
Enediyne sulfones 12-16 undergo a base-catalyzed isomerization to the corresponding enyne allenes followed by a tandem enyne allene-radical cyclization at 37°C to provide 2,3-dihydrobenz[e]indenes 17-21 in good yields.
