185909-51-7

Downstream Products

• 185909-52-8 (2Z,8E,10E)-(5S,7S)-12-Hydroxy-5-methoxy-7-(4-methoxy-benzyloxy)-2-methyl-dodeca-2,8,10-trienoic acid ethyl ester 
• 866476-35-9 (2E,4Z)-6-(benzyloxy)-4-bromohexa-2,4-dien-1-ol 
• 1011243-11-0 C₅₁H₈₄BrO₁₅PSi 
• 1011243-16-5 (3S,7S,8R,10E,12E,15R,17E,19E)-21-hydroxy-7,15-bis(4-methoxybenzyloxy)-8-methyl-9-oxohenicosa-10,12,17,19-tetraen-3-yl 2-(diethoxyphosphoryl)acetate 
• 1011243-20-1 (5S,6R,8E,10E,13R,15E,17E)-19-hydroxy-5,13-bis(4-methoxybenzyloxy)-6-methyl-7-oxononadeca-8,10,15,17-tetraenyl 2-(diethoxyphosphoryl)acetate 

Relevant academic research and scientific papers

An improved synthesis of (2E,4Z)-6-(benzyloxy)-4-bromohexa-2,4-dien-1-ol

An improved synthesis of (2E,4Z)-6-(benzyloxy)-4-bromohexa-2,4-dien-1-ol has been devised. This new route increases the throughput and yield of the diene product by circumventing a low yielding preparation of boronic acid intermediate as well as removing the need to use multi-gram quantities of highly toxic thallium salts. In the process of developing this new route, a higher yielding preparation of (E)-3-hydroxyprop-1-enylboronic acid was also achieved.