185985-40-4

Basic information

• Product Name: 2,3-dichloro-5-fluoropyridine
• Synonyms: AC-5997;Pyridine,2,3-dichloro-5-fluoro;2,3,5-TRIFLUOROBENZYL CYANIDE;ABBYPHARMA AP-31-5779
• CAS NO: 185985-40-4
• Molecular Formula: C5H2Cl2FN
• Molecular Weight: 165.98
• EINECS: 251-156-6
• Product Categories: Fluorine series
• Mol File: 185985-40-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 174.028 °C at 760 mmHg
• Flash Point: 59.05 °C
• Appearance: /Solid
• Density: 1.498 g/cm³
• Vapor Pressure: 1.65mmHg at 25°C
• Refractive Index: 1.528
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -2.97±0.10(Predicted)
• Water Solubility: Slightly soluble in chloroform, methanol and water.
• CAS DataBase Reference: 2,3-dichloro-5-fluoropyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-dichloro-5-fluoropyridine(185985-40-4)
• EPA Substance Registry System: 2,3-dichloro-5-fluoropyridine(185985-40-4)

Safety Data

• Hazardous Substances Data: 185985-40-4(Hazardous Substances Data)

Usage

Uses

2,3-Dichloro-5-fluoropyridine is a reagent that is used in the synthesis of 3-Chloro-5-fluoro Clodinafop Propargyl (C368645), which is an impurity of Clodinafop Propargyl (C584515).

InChI:InChI=1/C5H2Cl2FN/c6-4-1-3(8)2-9-5(4)7/h1-2H

Upstream product

• 540-80-7 tert.-butylnitrite 
• 98121-41-6 5-Amino-2,3-dichloropyridine 
• 136888-21-6 2-chloro-5-fluoro-3-nitro pyridine 
• 884495-37-8 2-chloro-5-fluoro-3-nitropyridine 

Downstream Products

• 21717-96-4 2-amino-5-fluoropyridine 
• 136888-21-6 2-chloro-5-fluoro-3-nitro pyridine 
• 884495-37-8 2-chloro-5-fluoro-3-nitropyridine 
• 212268-12-7 2-amino-5-fluoro-3-nitropyridine 

Relevant articles and documents

ACYLGUANIDINE DERIVATIVE

An object of the present invention is to provide an excellent agent for treating or preventing dementia, schizophrenia based on a serotonin 5-HT5A receptor modulating action. It was confirmed that acylguanidine derivatives, which has the charac