185994-16-5Relevant academic research and scientific papers
Design and synthesis of 2'-hydroxyethylcyclopropyl carbocyclic nucleosides
Yang, Te-Fang,Kim, Hongbum,Kotra, Lakshmi P.,Chu, Chung K.
, p. 8849 - 8852 (1996)
The enantiomeric synthesis of β-D-cyclopropyl carbocyclic nucleosides was achieved via the key intermediate 5. Thymine and uracil derivatives 7 and 9 were obtained by oxidation, Curtius rearrangement and the standard construction method of pyrimidines. The cytosine derivative 10 was prepared from 9 via the 4-triazole intermediate. Copyright (C) 1996 Elsevier Science Ltd.
