Tetrahedron Letters p. 8849 - 8852 (1996)
Update date:2022-08-05
Topics:
Yang, Te-Fang
Kim, Hongbum
Kotra, Lakshmi P.
Chu, Chung K.
The enantiomeric synthesis of β-D-cyclopropyl carbocyclic nucleosides was achieved via the key intermediate 5. Thymine and uracil derivatives 7 and 9 were obtained by oxidation, Curtius rearrangement and the standard construction method of pyrimidines. The cytosine derivative 10 was prepared from 9 via the 4-triazole intermediate. Copyright (C) 1996 Elsevier Science Ltd.
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