1860-83-9Relevant academic research and scientific papers
SYNTHESIS AND PROPERTIES OF FURAN DERIVATIVES. 4. SYNTHESIS OF 2,5-DISUBSTITUTED 1,3,4-OXADIAZOLES CONTAINING FURAN FRAGMENTS
Karakhanov, R. A.,Kelarev, V. I.,Koshelev, V. N.,Morozova, G. V.,Dibi, Ammar
, p. 208 - 218 (1995)
The condensation of hydrochloride salts of iminoesters of furan acids with hydrazides of carboxylic acids gives 2,5-disubstituted 1,3,4-oxadiazoles containing furan fragments.Such compounds are also formed in the condensation of hydrazides of 5-R-furan-2-carboxylic acids with hydrochloride salts of carboxylic acid iminoesters.The reaction of furan acids with hydrazine dihydrochloride in polyphosphoric acid gave symmetrically disubstituted 1,3,4-oxadiazoles containing furan fragments.
PREPARATION OF 2- AND 2,5-DISUBSTITUTED 1,3,4-OXADIAZOLES FROM TETRAZOLES AND CARBOXYLIC ACIDS
Povazanec, Frantisek,Kovac, Jaroslav,Svoboda, Jozef
, p. 1299 - 1300 (2007/10/02)
The intermediate N-acylated tetrazoles, prepared from 5-substituted tetrazoles, N,N'-dicyclohexylcarbodiimide and carboxylic acids, undergo decomposition to form 2-, or 2,5-disubstituted 1,3,4-oxadiazoles in high yield.
