186000-42-0

Basic information

• Product Name: 3-CHLOROPHENYLZINC IODIDE
• Synonyms: 3-CHLOROPHENYLZINC IODIDE;3-CHLOROPHENYLZINC IODIDE, 0.5M SOLUTION IN TETRAHYDROFURAN;3-chlorophenylzinc iodide solution;3-Chlorophenylzinc iodide solution 0.5 in THF;3-Chlorophenylzinc iodide, 0.5M in THF, packaged under Argon in resealable CheMSeal^t bottles;3-Chlorophenylzinc iodide, Packaged under Argon in resealable ChemSeal? bottles;3-Chlorophenylzinc iodide solution 0.5M in THF
• CAS NO: 186000-42-0
• Molecular Formula: C6H4ClIZn
• Molecular Weight: 303.84
• Product Categories: Aryl;Organozinc Halides;Reike and Organozinc Reagents
• Mol File: 186000-42-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: 1 °F
• Appearance: /
• Density: 1.032 g/mL at 25 °C
• Storage Temp.: 2-8°C
• Sensitive: Air Sensitive
• CAS DataBase Reference: 3-CHLOROPHENYLZINC IODIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CHLOROPHENYLZINC IODIDE(186000-42-0)
• EPA Substance Registry System: 3-CHLOROPHENYLZINC IODIDE(186000-42-0)

Safety Data

• Hazard Codes: F,Xn
• Statements: 11-19-22-36/37/38-40-36/37
• Safety Statements: 16-26-33-36-36/37
• RIDADR: UN 2056 3/PG 2
• WGK Germany: 1
• HazardClass: 4.3
• Hazardous Substances Data: 186000-42-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-Chlorophenylzinc iodide is used as a chemical intermediate for the synthesis of pharmaceuticals. Its ability to participate in a wide range of reactions makes it a valuable tool for synthetic chemists in creating new and complex organic compounds with potential therapeutic applications.
Used in Agrochemical Industry:
3-Chlorophenylzinc iodide is used as a chemical intermediate in the synthesis of agrochemicals. Its versatility in cross-coupling reactions allows for the development of new compounds with improved efficacy and selectivity in agricultural applications.
Used in Organic Synthesis:
3-Chlorophenylzinc iodide is used as a reagent in organic synthesis for the formation of carbon-carbon bonds through cross-coupling reactions. This capability makes it an essential component in the creation of complex organic molecules for various applications, including materials science, chemical research, and the development of new compounds with specific properties.

InChI:InChI=1/C6H4Cl.HI.Zn/c7-6-4-2-1-3-5-6;;/h1-2,4-5H;1H;/q;;+1/p-1/rC6H4ClIZn/c7-5-2-1-3-6(4-5)9-8/h1-4H

Upstream product

• 625-99-0 3-iodochlorobenzene 
• 7440-66-6 zinc 

Relevant articles and documents

Ni-Catalyzed Regioselective β,δ-Diarylation of Unactivated Olefins in Ketimines via Ligand-Enabled Contraction of Transient Nickellacycles: Rapid Access to Remotely Diarylated Ketones

We disclose a [(PhO)3P]/NiBr2-catalyzed regioselective β, δ-diarylation of unactivated olefins in ketimines with aryl halides and arylzinc reagents. This diarylation proceeds at remote locations to the carbonyl group to afford, after simple H+ workup, diversely substituted β, δ-diarylketones that are otherwise difficult to access readily with existing methods. Deuterium-labeling and crossover experiments indicate that diarylation proceeds by ligand-enabled contraction of transient nickellacycles.

Ni-Catalyzed Regioselective Dicarbofunctionalization of Unactivated Olefins by Tandem Cyclization/Cross-Coupling and Application to the Concise Synthesis of Lignan Natural Products

We disclose a (terpy)NiBr2-catalyzed reaction protocol that regioselectively difunctionalizes unactivated olefins with tethered alkyl halides and arylzinc reagents. The reaction shows an excellent functional group tolerance (such as ketones, es

Synergistic Bimetallic Ni/Ag and Ni/Cu Catalysis for Regioselective γ,δ-Diarylation of Alkenyl Ketimines: Addressing β-H Elimination by in Situ Generation of Cationic Ni(II) Catalysts

We disclose unprecedented synergistic bimetallic Ni/Ag and Ni/Cu catalysts for regioselective γ,δ-diarylation of unactivated alkenes in simple ketimines with aryl halides and arylzinc reagents. The bimetallic synergy, which generates cationic Ni(II) speci