186000-42-0 Usage
Description
3-Chlorophenylzinc iodide is a chemical compound that consists of a zinc atom bonded to a 3-chlorophenyl group and an iodide ion. It is a versatile zinc organometallic reagent commonly used as a reagent in organic chemistry reactions, particularly in cross-coupling reactions to form carbon-carbon bonds.
Uses
Used in Pharmaceutical Industry:
3-Chlorophenylzinc iodide is used as a chemical intermediate for the synthesis of pharmaceuticals. Its ability to participate in a wide range of reactions makes it a valuable tool for synthetic chemists in creating new and complex organic compounds with potential therapeutic applications.
Used in Agrochemical Industry:
3-Chlorophenylzinc iodide is used as a chemical intermediate in the synthesis of agrochemicals. Its versatility in cross-coupling reactions allows for the development of new compounds with improved efficacy and selectivity in agricultural applications.
Used in Organic Synthesis:
3-Chlorophenylzinc iodide is used as a reagent in organic synthesis for the formation of carbon-carbon bonds through cross-coupling reactions. This capability makes it an essential component in the creation of complex organic molecules for various applications, including materials science, chemical research, and the development of new compounds with specific properties.
Check Digit Verification of cas no
The CAS Registry Mumber 186000-42-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,6,0,0 and 0 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 186000-42:
(8*1)+(7*8)+(6*6)+(5*0)+(4*0)+(3*0)+(2*4)+(1*2)=110
110 % 10 = 0
So 186000-42-0 is a valid CAS Registry Number.
InChI:InChI=1/C6H4Cl.HI.Zn/c7-6-4-2-1-3-5-6;;/h1-2,4-5H;1H;/q;;+1/p-1/rC6H4ClIZn/c7-5-2-1-3-6(4-5)9-8/h1-4H
186000-42-0Relevant articles and documents
Ni-Catalyzed Regioselective β,δ-Diarylation of Unactivated Olefins in Ketimines via Ligand-Enabled Contraction of Transient Nickellacycles: Rapid Access to Remotely Diarylated Ketones
Basnet, Prakash,Dhungana, Roshan K.,Thapa, Surendra,Shrestha, Bijay,Kc, Shekhar,Sears, Jeremiah M.,Giri, Ramesh
, p. 7782 - 7786 (2018/06/22)
We disclose a [(PhO)3P]/NiBr2-catalyzed regioselective β, δ-diarylation of unactivated olefins in ketimines with aryl halides and arylzinc reagents. This diarylation proceeds at remote locations to the carbonyl group to afford, after simple H+ workup, diversely substituted β, δ-diarylketones that are otherwise difficult to access readily with existing methods. Deuterium-labeling and crossover experiments indicate that diarylation proceeds by ligand-enabled contraction of transient nickellacycles.
Synergistic Bimetallic Ni/Ag and Ni/Cu Catalysis for Regioselective γ,δ-Diarylation of Alkenyl Ketimines: Addressing β-H Elimination by in Situ Generation of Cationic Ni(II) Catalysts
Basnet, Prakash,Kc, Shekhar,Dhungana, Roshan K.,Shrestha, Bijay,Boyle, Timothy J.,Giri, Ramesh
supporting information, p. 15586 - 15590 (2018/11/23)
We disclose unprecedented synergistic bimetallic Ni/Ag and Ni/Cu catalysts for regioselective γ,δ-diarylation of unactivated alkenes in simple ketimines with aryl halides and arylzinc reagents. The bimetallic synergy, which generates cationic Ni(II) speci
