186023-39-2

Basic information

• Product Name: L-Serine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-, phenylmethyl ester
• CAS NO: 186023-39-2
• Molecular Formula: C30H32N2O6
• Molecular Weight: 516.594
• Mol File: 186023-39-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: L-Serine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Serine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-, phenylmethyl ester(186023-39-2)
• EPA Substance Registry System: L-Serine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-, phenylmethyl ester(186023-39-2)

Safety Data

• Hazardous Substances Data: 186023-39-2(Hazardous Substances Data)

Upstream product

• 1220106-68-2 C₃₇H₃₆N₂O₇ 
• 68858-20-8 Fmoc-Val-OH 
• 60022-62-0 L-serine benzyl ester hydrochloride 

Downstream Products

• 186023-48-3 (S)-3-[(S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-methyl-butyryl]-2,2-dimethyl-oxazolidine-4-carboxylic acid benzyl ester 
• 186023-51-8 ((S)-1-{(S)-2-(4-Methoxy-phenyl)-4-[(S)-1-(4-nitro-phenylcarbamoyl)-2-phenyl-ethylcarbamoyl]-oxazolidine-3-carbonyl}-2-methyl-propyl)-carbamic acid 9H-fluoren-9-ylmethyl ester 
• 204502-22-7 (S)-3-[(S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-methyl-butyryl]-2-(4-methoxy-phenyl)-oxazolidine-4-carboxylic acid 
• 186023-50-7 (S)-3-((S)-2-Amino-3-methyl-butyryl)-2,2-dimethyl-oxazolidine-4-carboxylic acid [(S)-1-(4-nitro-phenylcarbamoyl)-2-phenyl-ethyl]-amide 
• 186023-49-4 Fmoc-Val-Ser(ΨMe,Me-pro)-OH 
• 831238-95-0 (S)-2-[(S)-1-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-methyl-propyl]-4,5-dihydro-oxazole-4-carboxylic acid benzyl ester 

Relevant articles and documents

Salicylaldehyde ester-induced chemoselective peptide ligations: Enabling generation of natural peptidic linkages at the serine/threonine sites

A serine/threonine-based chemoselective ligation method is described. It uses an O-salicylaldehyde ester at the C-terminus, reacting with N-terminal serine or threonine to realize peptide ligations. The utility of the O-salicylaldehyde ester enables the rapid coupling reaction and the production of an N,O-benzylidene acetal intermediate, which is readily converted into natural peptidic linkages (Xaa-Ser/Thr) at the ligation site.