18607-93-7

Basic information

• Product Name: Sarisan
• Synonyms: Sarisan;asaricin,5-methoxy-6-(2-propenyl)-1,3-benzodioxole,sarisan;5-Allyl-6-methoxy-1,3-benzodioxole;5-Methoxy-6-(2-propenyl)-1,3-benzodioxole;Asaricin;Asaricine
• CAS NO: 18607-93-7
• Molecular Formula: C₁₁H₁₂O₃
• Molecular Weight: 192.21
• Mol File: 18607-93-7.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 259.4°Cat760mmHg
• Flash Point: 85.3°C
• Appearance: /
• Density: 1.137g/cm³
• Vapor Pressure: 0.021mmHg at 25°C
• Refractive Index: 1.539
• CAS DataBase Reference: Sarisan(CAS DataBase Reference)
• NIST Chemistry Reference: Sarisan(18607-93-7)
• EPA Substance Registry System: Sarisan(18607-93-7)

Safety Data

• Hazardous Substances Data: 18607-93-7(Hazardous Substances Data)

Usage

General Description

Sarisan is a chemical compound used as an offensive/defensive chemical warfare agent. Its colorless and odorless nature makes it difficult to detect and can be lethal in high concentrations. It works by inhibiting the action of acetylcholinesterase, an enzyme that breaks down acetylcholine, which leads to a buildup of this neurotransmitter and disrupts nerve cell function. It is frequently categorized as a nerve gas and it’s known for its fast-acting effects on the human body. Its use can cause a range of symptoms from vision problems and breathing difficulties to muscle weakness, seizures, or even death in more severe cases.

InChI:InChI=1/C11H12O3/c1-3-4-8-5-10-11(14-7-13-10)6-9(8)12-2/h3,5-6H,1,4,7H2,2H3

Upstream product

• 74-83-9 methyl bromide 
• 19202-23-4 5-hydroxy-6-(2-propenyl)-1,3-benzodioxole 
• 627-40-7 methylallylether 
• 533-31-3 Sesamol 
• 19202-22-3 O-allyl-sesamol 
• 762-72-1 allyl-trimethyl-silane 
• 74730-21-5 4S-(+)-illicinone-A 
• 74-88-4 methyl iodide 
• 67-56-1 methanol 

Downstream Products

• 194605-01-1 1,2-methylenedioxy-5-methoxy-4-trans-propenylbenzene 
• 117885-70-8 5-(2,3-dibromo-propyl)-6-methoxy-benzo[1,3]dioxole 

Relevant articles and documents

Pyrazolyl asarin derivative and preparation method and application thereof

The invention discloses a pyrazolyl asarin derivative, a preparation method thereof and application of the pyrazolyl asarin derivative as a bacteriostatic agent, the chemical structure of the pyrazolyl asarin derivative is shown as a general formula (f), and R is selected from hydrogen, C1-C5 alkyl, cyano, nitro or halogen. Compared with the prior art, the novel pyrazolyl asarin derivative provided by the invention has good antibacterial activity, and the compound is cheap and easy to obtain. Part of target asarin derivatives particularly have relatively strong inhibitory activity on fusarium graminearum, valsa mali, watermelon fusarium wilt and pumpkin fusarium wilt, and are expected to be used for preparing novel natural product bacteriostatic agents.

Domino Processes of Arynes Reacting with Three Classes of Nucleophiles for Organic Syntheses

Synthetic application of arynes is broadened by their reactions with neutral N-, S-, and O-containing nucleophiles to produce three types of compounds. Accordingly, 1,2-dihydroquinolines are synthesized from Schiff bases, alkynes, and arynes through a Diels-Alder reaction. Epoxides are prepared from thioethers and arynes along with aldehydes or ketones through a Johnson-Corey-Chaykovsky reaction. Phenolic ethers are produced from allyl ethers and arynes through a Claisen-type rearrangement. These target molecules, including natural products γ-asarone, asaricin, and a cholesteryl phenolic ether, are formed through reactions initiated by arynes. These new reactions share a prevailing feature of domino processes, which are carried out in a single flask and afford the desired products in good to high yields.

Expeditious synthesis of bioactive allylphenol constituents of the genus Piper through a metal-free photoallylation procedure

Nine bioactive allylphenol (anisole) derivatives (e.g. eugenol, safrole and asaricin) present in several plants of the genus Piper have been synthesized in medium to high yield via aryl cation intermediates. This expeditious metal-free procedure involves the irradiation of the corresponding chlorophenols or chloroanisoles in a polar solvent (MeCN or, better, TFE or aqueous acetonitrile) in the presence of allyltrimethylsilane. Estragole has also been synthesized starting from the corresponding fluoroderivative and diazonium salt, though in a lower yield. The Royal Society of Chemistry 2005.