1861-01-4

Basic information

• Product Name: ETHYL-ALPHA,ALPHA-D2-BENZENE
• Synonyms: ETHYL-ALPHA,ALPHA-D2-BENZENE;ETHYL-1,1-D2-BENZENE;ETHYL-1,1-D2-BENZENE 97%;Ethyl-α,α-D2-benzene;Ethyl-a,a-d2-benzene
• CAS NO: 1861-01-4
• Molecular Formula: C₈H₁₀
• Molecular Weight: 108.18
• Product Categories: Alphabetical Listings;E-F;Stable Isotopes
• Mol File: 1861-01-4.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 136 °C(lit.)
• Flash Point: 72 °F
• Appearance: /
• Density: 0.883 g/mL at 25 °C
• CAS DataBase Reference: ETHYL-ALPHA,ALPHA-D2-BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL-ALPHA,ALPHA-D2-BENZENE(1861-01-4)
• EPA Substance Registry System: ETHYL-ALPHA,ALPHA-D2-BENZENE(1861-01-4)

Safety Data

• Hazard Codes: F
• Statements: 11
• Safety Statements: 16
• Hazardous Substances Data: 1861-01-4(Hazardous Substances Data)

Usage

Uses

Ethyl-alpha,alpha-d2-benzene (CAS# 1861-01-4) is a useful isotopically labeled research compound.

Upstream product

• 41203-27-4 1-chloro-1-deuterio-1-phenylethane 
• 98-86-2 acetophenone 
• 98-85-1 1-Phenylethanol 
• 3101-96-0 1-deuterio-1-phenylethanol 
• 74-88-4 methyl iodide 
• 100-41-4 ethylbenzene 
• 1861-02-5 1-deuterioethylbenzene 

Downstream Products

• 908013-49-0 (1R)-[N-(p-toluenesulfonyl)-p-toluenesulfonimidoyl]-1-aminoethylbenzene 
• 1259394-60-9 C₂₂H₂₃⁽²⁾HN₂O₃S₂ 
• 150713-41-0 1-(1-2H₂)ethyl-2-nitrobenzene 
• 71886-64-1 (S)-α-Deuterio-α-phenylethanol 
• 71886-65-2 1-deuterio-(R)-(+)-1-phenylethanol 
• 3101-96-0 1-deuterio-1-phenylethanol 

Relevant articles and documents

A Convenient and Selective Method for Reductive Deuteriation of Aryl Carbonyl Compounds

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Room-Temperature Palladium-Catalyzed Deuterogenolysis of Carbon Oxygen Bonds towards Deuterated Pharmaceuticals

Site-specific incorporation of deuterium into drug molecules to study and improve their biological properties is crucial for drug discovery and development. Herein, we describe a palladium-catalyzed room-temperature deuterogenolysis of carbon–oxygen bonds

Photocatalytic transfer hydrogenolysis of aromatic ketones using alcohols

A mild method of photocatalytic deoxygenation of aromatic ketones to alkyl arenes was developed, which utilized alcohols as green hydrogen donors. No hydrogen evolution during this transformation suggested a mechanism of direct hydrogen transfer from alcohols. Control experiments with additives indicated the role of acid in transfer hydrogenolysis, and catalyst characterization confirmed a larger number of Lewis acidic sites on the optimal Pd/TiO2 photocatalyst. Hence, a combination of hydrogen transfer sites and acidic sites may be responsible for efficient deoxygenation without additives. The photocatalyst showed reusability and achieved selective reduction in a variety of aromatic ketones.

Selective sp3 C-H bond activation of alkylaromatics promoted by platinum complexes

Facile sp3 C-H bond activation of toluene, p-xylene and mesitylene, was photochemically promoted by trans-Pt(CH2CMe2Et)Br(PPh3)2 leading to trans-Pt(CH2Ar)Br(PPh3)2 quantitatively, while regioselective sp3 C-H bond cleavage at the benzylic position of ethylbenzene and cumene readily took place to yield styrene and α-methylstyrene, respectively.A possible reaction mechanism involving radical process is discussed on the basis of isotope and radical-trap experiments. Key words: Platinum; Benzyl; Bond activation; Radical; Photochemistry