186146-35-0Relevant academic research and scientific papers
Enantioselective Synthesis of α-Hydroxyketones using the DiTOX Asymmetric Building Block
Page, Philip C. Bulman,Purdle, Mark,Lathbury, David
, p. 8929 - 8932 (2007/10/03)
The 2-(R)- and 2-(S)-hydroxy-1-phenylbutan-1-ones have been prepared in high enantiomeric excesses and in five steps from propanal using a dithiane oxide unit as an asymmetric building block and a modified Sharpless enantioselective sulphur oxidation as the source of chirality.
