186249-73-0Relevant academic research and scientific papers
Asymmetric aziridination by reaction of chiral N-sulfinylimines with sulfur ylides: Stereoselectivity improvement by use of tert-butylsulfinyl group as chiral auxiliary
Garcia Ruano, Jose L.,Fernandez, Inmaculada,Del Prado Catalina, Miriam,Alcudia Cruz, Ana
, p. 3407 - 3414 (1996)
Chiral tert-butylsulfinyl group has been shown to be the chiral auxiliary of choice for the asymmetric aziridination of N-sulfinyliminas. Moreover, the sense of the asymmetric induction can be tuned in two ways: the chirality at the tert-butylsulfinyl Sulfur, or the nature of the methylene transfer reagent used. Thus, both aziridines 10(S(S),S) and 10(R(S),R), epimeric at C-2, were obtained in enantiomerically pure form by a single crystallisation (75% yield).
Asymmetric radical alkylation of: N -sulfinimines under visible light photocatalytic conditions
Garrido-Castro, Alberto F.,Choubane, Houcine,Daaou, Mortada,Maestro, M. Carmen,Alemán, José
supporting information, p. 7764 - 7767 (2017/07/13)
In this communication, a new photocatalytic strategy for the addition of alkyl-radical derivatives to N-sulfinimines with complete diastereoselectivity and moderate to good yields is presented. This is the first asymmetric photocatalytic addition to N-sulfinimines under visible light irradiation with smooth conditions and functional group tolerance.
