186265-00-9

Upstream product

• 147716-82-3 syringolide 1 
• 100-51-6 benzyl alcohol 

Downstream Products

• 186265-11-2 Succinic acid mono-((3R,3aS,5R,5aS,8aR)-5-benzyloxy-6-oxo-5-pentyl-tetrahydro-difuro[3,2-b;3',4'-c]furan-3-yl) ester 
• 186265-09-8 3-(4-Methoxy-phenyl)-propionic acid (3R,3aS,5R,5aS,8aR)-5-benzyloxy-6-oxo-5-pentyl-tetrahydro-difuro[3,2-b;3',4'-c]furan-3-yl ester 
• 186265-07-6 (3,4,5-Trimethoxy-phenyl)-acetic acid (3R,3aS,5R,5aS,8aR)-5-benzyloxy-6-oxo-5-pentyl-tetrahydro-difuro[3,2-b;3',4'-c]furan-3-yl ester 
• 186265-15-6 (3,4,5-Trimethoxy-phenyl)-acetic acid (3R,3aS,5R,5aS,8aR)-5-hydroxy-6-oxo-5-pentyl-tetrahydro-difuro[3,2-b;3',4'-c]furan-3-yl ester 

Relevant academic research and scientific papers

Synthesis of syringolide 1 ketals and esters for receptor studies

The syringolides, specified by avirulence gene D from Pseudomonas syringae, elicit a disease defense reaction only in soybean cultivars carrying the Rpg4 disease resistance gene. In order to identify structural features important for elicitor activity and construct highly labelled elicitor-active probes, several syringolide esters and ketals were synthesized. Alteration of the C-3 hemiketal group of syringolide 1 abolished elicitor activity, but ester derivatives based on the C-4' hydroxy group all retained activity. [125I]4'-(2-iodo-3,4,5-trimethoxyphenylacetyl) syringolide 1 was prepared for receptor studies.