186265-11-2

Upstream product

• 108-30-5 succinic acid anhydride 
• 186265-00-9 (3R,3aS,5R,5aS,8aR)-5-Benzyloxy-3-hydroxy-5-pentyl-tetrahydro-difuro[3,2-b;3',4'-c]furan-6-one 
• 100-51-6 benzyl alcohol 
• 147716-82-3 syringolide 1 

Relevant academic research and scientific papers

Synthesis of syringolide 1 ketals and esters for receptor studies

The syringolides, specified by avirulence gene D from Pseudomonas syringae, elicit a disease defense reaction only in soybean cultivars carrying the Rpg4 disease resistance gene. In order to identify structural features important for elicitor activity and construct highly labelled elicitor-active probes, several syringolide esters and ketals were synthesized. Alteration of the C-3 hemiketal group of syringolide 1 abolished elicitor activity, but ester derivatives based on the C-4' hydroxy group all retained activity. [125I]4'-(2-iodo-3,4,5-trimethoxyphenylacetyl) syringolide 1 was prepared for receptor studies.