186265-11-2Relevant articles and documents
Synthesis of syringolide 1 ketals and esters for receptor studies
Tsurushima, Tetsu,Midland, Sharon L.,Zeng, Chun-Min,Ji, Cheng,Sims, James J.,Keen, Noel T.
, p. 1219 - 1225 (2007/10/03)
The syringolides, specified by avirulence gene D from Pseudomonas syringae, elicit a disease defense reaction only in soybean cultivars carrying the Rpg4 disease resistance gene. In order to identify structural features important for elicitor activity and construct highly labelled elicitor-active probes, several syringolide esters and ketals were synthesized. Alteration of the C-3 hemiketal group of syringolide 1 abolished elicitor activity, but ester derivatives based on the C-4' hydroxy group all retained activity. [125I]4'-(2-iodo-3,4,5-trimethoxyphenylacetyl) syringolide 1 was prepared for receptor studies.