186382-52-5Relevant academic research and scientific papers
A convenient approach to the aminocyclitol fragment of pancratistatin from 7-oxanorbornenes
Acena, Jose Luis,Arjona, Odon,Iradier, Fatima,Plumet, Joaquin
, p. 105 - 106 (1996)
A totally stereoselective route to an analogue aminocyclitol fragment of the alkaloid pancratistatin has been achieved starting from a 7-oxanorbornenic disulfone. The key step was the alkylative cleavage of the oxygen bridge to produce a highly oxygenated cyclohexenyl sulfone.
Total synthesis of (+)-pinitol
Acena, Jose Luis,Arjona, Odon,Plumet, Joaquin
, p. 3535 - 3544 (2007/10/03)
A new synthesis of (+)-pinitol 9 has been developed starting from the 7-oxanorbornenic sulfone (+)-5, prepared in enantiomerically pure form by resolution of the sulfonyl-7-oxanorbornanol 4. These precursors are available from the Diels-Alder adduct of furan and trans-1,2-bis-(phenylsulfonyl)-ethylene.
