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CAS

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186388-08-9

2-benzyl-4-(3-chloro-propyl)-6-methyl-2H-[1,2,4]triazine-3,5-dione is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 186388-08-9 Structure

  • Basic information

    1. Product Name: 2-benzyl-4-(3-chloro-propyl)-6-methyl-2H-[1,2,4]triazine-3,5-dione
    2. Synonyms: 2-benzyl-4-(3-chloro-propyl)-6-methyl-2H-[1,2,4]triazine-3,5-dione
    3. CAS NO:186388-08-9
    4. Molecular Formula:
    5. Molecular Weight: 293.753
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 186388-08-9.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-benzyl-4-(3-chloro-propyl)-6-methyl-2H-[1,2,4]triazine-3,5-dione(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-benzyl-4-(3-chloro-propyl)-6-methyl-2H-[1,2,4]triazine-3,5-dione(186388-08-9)
    11. EPA Substance Registry System: 2-benzyl-4-(3-chloro-propyl)-6-methyl-2H-[1,2,4]triazine-3,5-dione(186388-08-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 186388-08-9(Hazardous Substances Data)

186388-08-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 186388-08-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,6,3,8 and 8 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 186388-08:
(8*1)+(7*8)+(6*6)+(5*3)+(4*8)+(3*8)+(2*0)+(1*8)=179
179 % 10 = 9
So 186388-08-9 is a valid CAS Registry Number.

186388-08-9Downstream Products

186388-08-9Relevant articles and documents

Synthesis, pharmacology and pharmacokinetics of 3-(4-Arylpiperazin-1-ylalkyl)-uracils as uroselective α1A-antagonists

Lopez,Arias,Chan,Clarke,Elworthy,Ford,Guzman,Jaime-Figueroa,Jasper,Morgans Jr.,Padilla,Perez-Medrano,Quintero,Romero,Sandoval,Smith,Williams,Blue

, p. 1873 - 1878 (2003)

Predominance in the urethra and prostate of the α1A-adrenoceptor subtype, which is believed to be the receptor mediating noradrenaline induced smooth muscle contraction in these tissues, led to the preparation of α1A-selective antagonists to be tested as uroselective compounds for the treatment of benign prostatic hyperplasia. Thus, a number of selective α1A-adrenoceptor antagonists were synthesized and assayed in vitro for potency and selectivity. Dog pharmacokinetic parameters of 12 (RO700004) and its metabolite 40 (RO1104253) were established. The relative selectivity of intravenously administered 12, 40 and standard prazosin to inhibit hypogastric nerve stimulation-induced increases in intraurethral prostatic pressure versus phenylephrine-induced increases in diastolic blood pressure in anesthetized dogs was 76, 71 and 0.6, respectively.

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