186393-28-2Relevant academic research and scientific papers
Preparation method of dichlorotoluene nitride intermediate
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Sheet 0033-0034; 0054; 0058-0059, (2021/01/28)
The invention belongs to the technical field of preparation of pesticide intermediates, and particularly discloses a preparation method of a dichlorotoluene nitride intermediate. The preparation method comprises the following steps: fully reacting raw materials, a solvent and a nitration reagent to obtain a dichlorotoluene nitride intermediate, wherein the raw materials comprise any one of o-dichlorotoluene, m-dichlorotoluene and p-dichlorotoluene; the solvent is dichloroethane; the nitration reagent is concentrated nitric acid; the dichlorotoluene nitride intermediate is shown as a chemical formula 7 and a chemical formula 12. The preparation method has the advantages that the corrosion to reaction equipment is less, and the generation and discharge of waste acid and waste salt in the production process are greatly reduced.
Aminophenyl derivatives as selective androgen receptor modulators
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Page/Page column 20, (2008/06/13)
Disclosed herein is a novel class of aminophenyl compounds having the structure: wherein R1 is cyano or nitro and ring A is a bi- or tricyclic bridged heterocycle and to their use as modulators of androgen receptor for the treatment or preventi
Process for the preparation of ethyl-N-(2,3 dichloro-6-nitrobenzyl) glycine
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, (2008/06/13)
The known blood platelet reducing agent Anagrelide is prepared via an improved process starting with commercially available 2,3-dichlorotoluene and involving novel intermediates represented by the formulas: STR1 wherein Y is Br, Cl or I. Compound (G) is r
