186429-12-9

Basic information

• Product Name: 2-Pyrrolidinone,4-(1-ethoxyethoxy)-,(4S)-(9CI)
• Synonyms: 2-Pyrrolidinone,4-(1-ethoxyethoxy)-,(4S)-(9CI)
• CAS NO: 186429-12-9
• Molecular Formula: C8H15NO3
• Molecular Weight: 0
• Product Categories: METHOXY
• Mol File: 186429-12-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Pyrrolidinone,4-(1-ethoxyethoxy)-,(4S)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyrrolidinone,4-(1-ethoxyethoxy)-,(4S)-(9CI)(186429-12-9)
• EPA Substance Registry System: 2-Pyrrolidinone,4-(1-ethoxyethoxy)-,(4S)-(9CI)(186429-12-9)

Safety Data

• Hazardous Substances Data: 186429-12-9(Hazardous Substances Data)

Upstream product

• 186429-07-2 Methanesulfonic acid (S)-3-benzylcarbamoyl-2-(1-ethoxy-ethoxy)-propyl ester 
• 186429-03-8 (S)-N-benzyl-3-(1-ethoxy)ethoxy-4-hydroxybutyramide 
• 186429-08-3 Methanesulfonic acid (S)-3-allylcarbamoyl-2-(1-ethoxy-ethoxy)-propyl ester 
• 186429-05-0 (S)-N-allyl-3-(1-ethoxy)ethoxy-4-hydroxybutyramide 
• 263164-11-0 (S)-3-(1-ethoxy)ethoxy-γ-butyrolactone 
• 186429-04-9 (S)-N-benzyl-4-(1-ethoxy)ethoxy-2-oxopyrrolidine 
• 186429-06-1 (S)-N-allyl-4-(1-ethoxy)ethoxy-2-oxopyrrolidine 

Downstream Products

• 68108-18-9 (4S)-4-hydroxypyrrolidin-2-one 

Relevant articles and documents

Efficient syntheses of (S)-4-hydroxy-2-pyrrolidinone derivatives

Efficient syntheses of (S)-4-hydroxy-2-pyrrolidinone ((5)-2) and (R)4- acetylthio-2-pyrrolidinone (S), which are key intermediates of oral carbapenem CS-834, were studied. The most efficient route to (S)-2 from (S)- 3-hydroxybutyrolactone (8) was accomplished in high yield via (S)-N-allyl-3- (1-ethoxy)ethoxy-4-hydroxybutyramide (14).