186456-57-5

Upstream product

• 186456-58-6 methyl 5-deoxy-2,3-di-O-(phenylmethyl)-D-ribofuranoside 
• 109-80-8 1.3-propanedithiol 

Downstream Products

• 592517-04-9 (2S,3S,4R)-1,3,4-Tris-benzyloxy-4-[1,3]dithian-2-yl-2-methyl-butan-2-ol 
• 186456-91-7 (2R,3S,4R)-1,3,4-Tris-benzyloxy-4-[1,3]dithian-2-yl-2-methyl-butan-2-ol 
• 186456-68-8 4-N-phenylamino-5-phenyl-7-(5'-deoxy-2',3'-O-isopropylidene-4'-C-methyl-β-D-ribo-furanosyl)pyrrolo[2,3-d]pyrimidine 
• 186456-62-2 (3S,4R)-3,4-dibenzyloxy-4-([1,3]dithian-2-yl)-2-methylbutan-2-ol 
• 186456-60-0 (3S,4R)-3,4-dibenzyloxy-4-([1,3]dithian-2-yl)-butan-2-one 

Relevant academic research and scientific papers

Adenosine kinase inhibitors. 5. Synthesis, enzyme inhibition, and analgesic activity of diaryl-erythro-furanosyltubercidin analogues

Adenosine is an endogenous neuromodulator that when produced in the central and the peripheral nervous systems has anticonvulsant, anti-inflammatory, and analgesic properties. However, efforts to use adenosine receptor agonists are plagued by dose-limitin

Stereoselective synthesis of 4-C-methyl-2,3,5-tri-O-benzyl-D-ribofuranose and 4-C-methyl-2,3,5-tri-O-benzyl-L-lyxofuranose

Sugar intermediates 4-C-methyl-2,3,5-tri-O-benzyl-D-ribofuranose (8b) and 4-C-methyl-2,3,5-tri-O-benzyl-L-lyxofuranose (8a) were synthesized by addition of alkylithium reagents to pentanones 3a,b. The nucleophilic additions proceeded with good stereoselectivity and good yields to give the titled compounds in four steps from perbenzylated methyl D-ribofuranoside and methyl 5′-deoxy-D-ribofuranoside.