18651-45-1

Upstream product

• 2295-58-1 flopropione 
• 93-97-0 benzoic acid anhydride 
• 108-73-6 3,5-dihydroxyphenol 

Downstream Products

• 74443-24-6 5-hydroxy-3,6,6-trimethylpyrano<2,3:7,8>flavone 
• 74443-26-8 5-hydroxy-3,6,6-trimethylpyrano<2,3:7,6>flavone 
• 74443-23-5 7-(1,1-Dimethylpropargyloxy)-5-hydroxy-3-methylflavone 
• 111301-29-2 7-propargyloxy-5-hydroxy-3-methylflavone 
• 20350-14-5 5,7-Dimethoxy-3-methylflavone 
• 74443-25-7 Acetic acid 3,8,8-trimethyl-4-oxo-2-phenyl-4H,8H-pyrano[2,3-f]chromen-5-yl ester 
• 74443-27-9 Acetic acid 2,2,7-trimethyl-6-oxo-8-phenyl-2H,6H-pyrano[3,2-g]chromen-5-yl ester 
• 111301-31-6 7-methoxy-5-propargyloxy-3-methylflavone 
• 111301-32-7 9-methoxy-3-methyl-2-phenyl-6H-4-oxobenzo-<1,2-b:3,4-b'>dipyran 
• 111301-30-5 5-hydroxy-3-methyl-2-phenyl-8H-4-oxobenzo-<1,2-b:5,6-b'>dipyran 

Relevant academic research and scientific papers

A Study of Base-catalysed Wessely-Moser Rearrangement of 5-Hydroxy-3,6",6"-trimethylpyranoflavone

5,7-Dihydroxy-3-methylflavone (2) reacts with 2-chloro-2-methyl-3-butyne in the presence of K2CO3, Me2CO and KI to give the corresponding 7-(1,1-dimethylpropargyl) ether (4), which on heating with N,N-dimethylaniline gives the angular (5) and linear (7) 2,2-dimethylpyrano derivatives in the ratio of 2:1.When the angular chromene (5) is treated with dil. alcoholic potash, Wessely-Moser rearrangement occurs to give the corresponding linear chromene (7) in 80percent yield. 1,1-Dimethylpropargylation of 2 using DMF in place of acetone, yields a mixture containing 7-propargylic ether (4), angular chromene (5) and linear chromene (7).