18652-74-9Relevant articles and documents
Catalytic enantioselective bromohydroxylation of cinnamyl alcohols
Li, Jing,Shi, Yian
, p. 13040 - 13046 (2021)
This work describes an effective enantioselective bromohydroxylation of cinnamyl alcohols with (DHQD)2PHAL as the catalyst and H2O as the nucleophile, providing a variety of corresponding optically active bromohydrins with up to 95% ee.
Method for synthesizing photoactive bromohydrin compound
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Paragraph 0106-0111, (2021/07/21)
The invention discloses a method for synthesizing a photoactive bromohydrin compound, which comprises the following steps: reacting cinnamyl alcohol as shown in a formula I, benzamide bromide as shown in a formula II, a quinine derivative, L-camphorsulfonic acid and water in a first organic solvent to obtain the bromohydrin compound as shown in a formula III. According to the method, raw materials are easy to synthesize, reaction conditions are mild, operation is easy and convenient, the yield reaches up to 47%-87%, enantioselectivity can generally reach 80% or above, and the highest point can even reach 95%.
From simple organobromides or olefins to highly value-added bromohydrins: A versatile performance of dimethyl sulfoxide
Song, Song,Huang, Xiaoqiang,Liang, Yu-Feng,Tang, Conghui,Li, Xinwei,Jiao, Ning
supporting information, p. 2727 - 2731 (2015/05/27)
A novel and efficient direct transformation of secondary bromides or olefins to highly value-added bromohydrins has been disclosed. Dimethyl sulfoxide (DMSO), a cheap and common solvent, performs its versatile role as a solvent, an essential oxidant, and also as an oxygen source in this bromohydrin synthesis.