Welcome to LookChem.com Sign In|Join Free

CAS

  • or

186551-71-3

7-methoxynaphthalene-2-sulfonic acid [1-(3-cyanobenzyl)-2-oxopyrrolidin-3-(S)-yl](N-tert-butyloxycarbonylpyrazol-3-ylmethyl)amide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

186551-71-3 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 186551-71-3 Structure

  • Basic information

    1. Product Name: 7-methoxynaphthalene-2-sulfonic acid [1-(3-cyanobenzyl)-2-oxopyrrolidin-3-(S)-yl](N-tert-butyloxycarbonylpyrazol-3-ylmethyl)amide
    2. Synonyms: 7-methoxynaphthalene-2-sulfonic acid [1-(3-cyanobenzyl)-2-oxopyrrolidin-3-(S)-yl](N-tert-butyloxycarbonylpyrazol-3-ylmethyl)amide
    3. CAS NO:186551-71-3
    4. Molecular Formula:
    5. Molecular Weight: 615.71
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 186551-71-3.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 7-methoxynaphthalene-2-sulfonic acid [1-(3-cyanobenzyl)-2-oxopyrrolidin-3-(S)-yl](N-tert-butyloxycarbonylpyrazol-3-ylmethyl)amide(CAS DataBase Reference)
    10. NIST Chemistry Reference: 7-methoxynaphthalene-2-sulfonic acid [1-(3-cyanobenzyl)-2-oxopyrrolidin-3-(S)-yl](N-tert-butyloxycarbonylpyrazol-3-ylmethyl)amide(186551-71-3)
    11. EPA Substance Registry System: 7-methoxynaphthalene-2-sulfonic acid [1-(3-cyanobenzyl)-2-oxopyrrolidin-3-(S)-yl](N-tert-butyloxycarbonylpyrazol-3-ylmethyl)amide(186551-71-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 186551-71-3(Hazardous Substances Data)

186551-71-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 186551-71-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,6,5,5 and 1 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 186551-71:
(8*1)+(7*8)+(6*6)+(5*5)+(4*5)+(3*1)+(2*7)+(1*1)=163
163 % 10 = 3
So 186551-71-3 is a valid CAS Registry Number.

186551-71-3Relevant articles and documents

Design and structure-activity relationships of potent and selective inhibitors of blood coagulation factor Xa

Ewing, William R.,Becker, Michael R.,Manetta, Vincent E.,Davis, Roderick S.,Pauls, Henry W.,Mason, Helen,Choi-Sledeski, Yong Mi,Green, Daniel,Cha, Don,Spada, Alfred P.,Cheney, Daniel L.,Mason, Jonathan S.,Maignan, Sebastien,Guilloteau, Jean-Pierre,Brown, Karen,Colussi, Dennis,Bentley, Ross,Bostwick, Jeff,Kasiewski, Charles J.,Morgan, Suzanne R.,Leadley, Robert J.,Dunwiddie, Christopher T.,Perrone, Mark H.,Chu, Valeria

, p. 3557 - 3571 (2007/10/03)

The discovery of a series of non-peptide factor Xa (FXa) inhibitors incorporating 3-(s)-amino-2-pyrrolidinone as a central template is described. After identifying compound 4, improvements in in vitro potency involved modifications of the liphophilic group and optimizing the angle of presentation of the amidine group to the S1 pocket of FXa. These studies ultimately led to compound RPR120844, a potent inhibitor of FXa (K1 = 7 nM) which shows selectivity for FXa over trypsin, thrombin, and several fibrinolytic serine proteinases. RPR120844 is an effective anticoagulant in both the rat model of FeCl2-induced carotid artery thrombosis and the rabbit model of jugular vein thrombus formation.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 186551-71-3