186586-71-0 Usage
Uses
Used in Pharmaceutical Industry:
(2S,3R)-CIS-3-METHYL-L-PROLINE ETHYL ESTER is used as a pharmaceutical intermediate for the development of drugs targeting various medical conditions. Its unique stereochemistry and functional groups may contribute to the design of novel therapeutic agents with improved efficacy and selectivity.
Used in Organic Synthesis:
(2S,3R)-CIS-3-METHYL-L-PROLINE ETHYL ESTER is used as a building block in organic synthesis for the creation of complex organic molecules. Its distinct structure allows for the synthesis of a wide range of compounds with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 186586-71-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,6,5,8 and 6 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 186586-71:
(8*1)+(7*8)+(6*6)+(5*5)+(4*8)+(3*6)+(2*7)+(1*1)=190
190 % 10 = 0
So 186586-71-0 is a valid CAS Registry Number.
186586-71-0Relevant academic research and scientific papers
New strategy for the synthesis of 3-substituted prolines
Karoyan, Philippe,Chassaing, Gerard
, p. 85 - 88 (2007/10/03)
Ring formation involving a 5-exo trig cyclization between a zinc enolate and a non activated double bond led to cis diastereoisomer of 3-substituted prolines. This cyclization was achieved with transfer of chirality onto the C-2 carbon when nitrogen was protected by an α-methylbenzyl group. Reprotonation of the lithium enolate of cis derivative yielded the trans diastereoisomer.
