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Usage

Uses

Used in Organic Chemistry Synthesis:
2-Fluoro-5-iodophenol is utilized as a building block in organic chemistry synthesis, providing a foundation for the creation of complex organic molecules. Its unique structure, featuring both fluorine and iodine atoms, contributes to its versatility and reactivity in various chemical reactions.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 2-Fluoro-5-iodophenol is employed as a key intermediate in the synthesis of various drugs. Its presence in the molecular structure of these drugs can influence their properties, such as solubility, stability, and biological activity, making it an important component in drug development.
Used in Agrochemical Development:
2-Fluoro-5-iodophenol also finds application in the agrochemical sector, where it is used in the synthesis of pesticides and other crop protection agents. Its unique properties can enhance the effectiveness of these chemicals, contributing to improved agricultural productivity and crop protection.
Used in Medicinal Chemistry Research:
As a valuable tool in medicinal chemistry, 2-Fluoro-5-iodophenol is used in research to explore its potential applications in the development of new therapeutic agents. Its unique structure allows for the investigation of its interactions with biological targets, potentially leading to the discovery of novel drugs with improved efficacy and selectivity.
Used in Material Science:
In the field of material science, 2-Fluoro-5-iodophenol is employed in the development of new materials with specific properties. Its incorporation into the molecular structure of these materials can influence their physical, chemical, and electronic properties, making it a valuable component in the design and synthesis of advanced materials.

InChI:InChI=1/C6H4FIO/c7-5-2-1-4(8)3-6(5)9/h1-3,9H

Upstream product

• 866683-41-2 2-fluoro-5-iodophenylboronic acid 

Relevant academic research and scientific papers

PYRIDYL DERIVATIVES AND THEIR USE AS MGLU5 RECEPTOR ANTAGONISTS

The present invention is directed toward pyridyl derivatives of formula (I) as antagonists of the mGlu5 receptor. As such the compounds may be useful for treatment or prevention of disorders remedied by antagonism of the mGlu5 receptor, wherein Ar is phenyl or napthyl each of which may be substituted by one or more C1-C4 alkyl, C1-C4 alkoxy, C1-C5 acyl, halo, amino, nitro, cyano, hydroxy, C1-C5 acylamino, C1-C4 alkylsulfonylamino, mono-, di- or trifluorinated C1-C3 alkyl, substituents which may be the same or different and may bear a CONH2, CONHCH3, CON(CH3)2, CO2H, CO2CH3, OCF3, CH2NHCOCH3, CH2NH2, CH2N(CH3)2, CH2CN, CH2OH, CH2NHSO2CH3, CH2N(CH3)(CH2)2 CN, CH2N(CH3)CH(CH3)2, CH2NHCH(CH3)2, CH2NH(CH2)2CH3, CH2NHCO2R4, CH2NHCH2CH3, CH2NHCH3 NHCOC(CH3)2, or N(S(O)2CH3)2 substituent; R1 is hydrogen, halo, R4, CN, C(NOH)R3, C(NO-R4)R3, (CH)2CO2R4 , (CH2)n OR3 , COR3 , CF3,SR4 , S(O)R4, S(O)2R4, COCH2CO2R3 , NHSO2R4 , NHCOR3, C(NOR3)NH2, CH2OCOR3,(CH2)n NH2, CON(CH3)2 (CH2)nNHCO2R4 , CO2R3, CONH2, CSNH2, C(NH)NHOR3, (CH2)nN(CH3)2, or CONHNHCOR3; R2 is 1,2-ethenediyl or 1,2-ethynediyl; R3 is hydrogen or C1-C4 alkyl; R4 is C1-C4 alkyl; and n is 0, 1, 2,3 or 4; or a pharmaceutically acceptable salt thereof, or an N-oxide thereof.