186666-77-3Relevant articles and documents
Structure-activity relationships of alkyl- and alkoxy-substituted 1,4- dihydroquinoxaline-2,3-diones: Potent and systemically active antagonists for the glycine site of the NMDA receptor
Cai, Sui Xiong,Kher, Sunil M.,Zhou, Zhang-Lin,Ilyin, Victor,Espitia, Stephen A.,Tran, Minhtam,Hawkinson, Jon E.,Woodward, Richard M.,Weber, Eckard,Keana, John F. W.
, p. 730 - 738 (2007/10/03)
We report on a series of alkyl- and alkoxy-substituted 1,4- dihydroquinoxaline-2,3-diones (QXs), prepared as a continuation of our structure-activity relationship (SAR) study of QXs as antagonists for the glycine site of the N-methyl-D-aspartate (NMDA) re