186759-64-8

Basic information

• Product Name: (+)-phenylmethyl [(1R)-1-({[(1,1-dimethylethyl)(dimethyl)silyl]oxy}methyl)prop-2-en-1-yl]carbamate
• Synonyms: (+)-phenylmethyl [(1R)-1-({[(1,1-dimethylethyl)(dimethyl)silyl]oxy}methyl)prop-2-en-1-yl]carbamate
• CAS NO: 186759-64-8
• Molecular Weight: 335.519
• Mol File: 186759-64-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (+)-phenylmethyl [(1R)-1-({[(1,1-dimethylethyl)(dimethyl)silyl]oxy}methyl)prop-2-en-1-yl]carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-phenylmethyl [(1R)-1-({[(1,1-dimethylethyl)(dimethyl)silyl]oxy}methyl)prop-2-en-1-yl]carbamate(186759-64-8)
• EPA Substance Registry System: (+)-phenylmethyl [(1R)-1-({[(1,1-dimethylethyl)(dimethyl)silyl]oxy}methyl)prop-2-en-1-yl]carbamate(186759-64-8)

Safety Data

• Hazardous Substances Data: 186759-64-8(Hazardous Substances Data)

Upstream product

• 69261-49-0 benzyl formylcarbamate 
• 1315128-01-8 (-)-phenylmethyl [(1R)-1-({[(1,1-dimethylethyl)(dimethyl)silyl]oxy}methyl)prop-2-en-1-yl]formylcarbamate 
• 501-53-1 benzyl chloroformate 
• 80656-34-4 N-<(benzoyloxy)carbonyl>-D,L-vinylglycine methyl ester 
• 98854-91-2 N-<(benzyloxy)carbonyl>-D-vinylglycine methyl ester 
• 91103-38-7 (R)-(1-hydroxymethallyl)carbamic acid benzyl ester 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 1315128-42-7 (+)-methyl (2E,6R)-7-{[(1,1-dimethylethyl)(dimethyl)silyl]oxy}-6-({[(phenylmethyl)oxy]carbonyl}amino)hept-2-enoate 
• 1315128-66-5 (+)-phenylmethyl (2R,5R)-2-({[(1,1-dimethylethyl)(dimethyl)silyl]oxy}methyl)-5-[2-(methyloxy)-2-oxoethyl]pyrrolidine-1-carboxylate 

Relevant articles and documents

Enantioselective syntheses of 2,5-disubstituted pyrrolidines based on iridium-catalyzed allylic aminations-total syntheses of alkaloids from amphibian skins

A broadly applicable route to trans-2,5-disubstituted pyrrolidines has been developed. Key steps are an asymmetric iridium-catalyzed allylic amination, a Suzuki-Miyaura coupling, and an intramolecular aza-Michael addition. Enantiomeric excesses in the range of 93-99 % ee have been achieved. Total syntheses of the alkaloids (-)-225 C, (+)- and (-)-223 H (xenovenine), (+)-223 AB, (+)-195 B, and (+)-223 R have been carried out as applications. Copyright

A flexible synthesis of azasugars and homoazasugars via olefin metathesis

A flexible synthesis of azasugars and homoazasugars from vinyl glycine methyl ester is described. The syntheses, which are based on ring closing olefin metathesis steps and stereocontrolled functionalizations of the formed double bonds, offer a broad vari