69261-49-0

Upstream product

• 1138-80-3 N-(Benzyloxycarbonyl)glycine 
• 621-84-1 O-benzyl carbamate 
• 15500-60-4 N,N-bis(trimethylsilyl)formamide 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 74597-66-3 trans-6-benzyloxycarbonylaminomethylene-2-methoxy-5,6-dihydro-2H-pyran 
• 111833-84-2 6-benzyloxycarbonylamino-2,5-dihydroxy-1-methoxyhexane 
• 111833-81-9 methyl 6-benzyloxycarbonylamino-3,4,6-trideoxy-α-D,L-threo-hexopyranoside 
• 1234693-04-9 (+)-phenylmethyl [(1S)-1-({[(1,1-dimethylethyl)(diphenyl)silyl]oxy}methyl)prop-2-en-1-yl]formylcarbamate 
• 1315127-97-9 phenylmethyl ((2E)-4-{[(1,1-dimethylethyl)(diphenyl)silyl]oxy}but-2-en-1-yl)formylcarbamate 
• 1315127-86-6 (+)-phenylmethyl formyl((1S)-1-{[(triphenylmethyl)oxy]methyl}prop-2-en-1-yl)carbamate 
• 1315127-88-8 phenylmethyl formyl{(2E)-4-[(triphenylmethyl)oxy]but-2-en-1-yl}carbamate 
• 1315128-16-5 phenylmethyl formyl((1R)-1-{[(triphenylmethyl)oxy]methyl}prop-2-en-1-yl)carbamate 
• 1315128-08-5 phenylmethyl formyl{(2E)-5-[(triphenylmethyl)oxy]pent-2-en-1-yl}carbamate 
• 1315179-34-0 (-)-phenylmethyl formyl((1S)-1-{2-[(triphenylmethyl)oxy]ethyl}prop-2-en-1-yl)carbamate 
• 1315128-06-3 phenylmethyl formyl((1R)-1-{2-[(triphenylmethyl)oxy]ethyl}prop-2-en-1-yl)carbamate 
• 1315128-01-8 (-)-phenylmethyl [(1R)-1-({[(1,1-dimethylethyl)(dimethyl)silyl]oxy}methyl)prop-2-en-1-yl]formylcarbamate 
• 1315128-03-0 phenylmethyl ((2E)-4-{[(1,1-dimethylethyl)(dimethyl)silyl]oxy}but-2-en-1-yl)formylcarbamate 
• 1315128-81-4 phenylmethyl [(1S)-1-({[(1,1-dimethylethyl)(dimethyl)silyl]oxy}methyl)prop-2-en-1-yl]formylcarbamate 

Relevant academic research and scientific papers

Metal-Free Stereoselective Synthesis of (E)- And (Z)-N-Monosubstituted β-Aminoacrylates via Condensation Reactions of Carbamates

N-monosubstituted β-aminoacrylates are building blocks, which have been used in the preparation of amino acids and pharmaceuticals. Two efficient, stereoselective methods of preparation, via acid- or base-promoted condensation reactions of carbamates, are described. The base-promoted reaction is E-selective, while acid catalysis can, through the choice of solvent, selectively form E or Z. The acid-catalyzed E-selective process proceeds through a crystallization obviating the need for chromatographic purification.

Oxidative photo-decarboxylation in the presence of mesoporous silicas

FSM-16, a mesoporous silica, was found to catalyze oxidative photo-decarboxylation of α-hydroxy carboxylic acid, phenyl acetic acid derivatives and N-acyl-protected α-amino acids to afford the corresponding carbonyl compounds. Furthermore, FSM-16 proved to be re-usable by re-calcination at 450°C after the reaction.

New Synthetic Method of Imides through Oxidative Photodecarboxylation Reaction of N-Protected α-Amino Acids with FSM-16

FSM-16, a mesoporous silica, was found to promote the oxidative photodearboxylation of N-acyl-protected α-amino acids in hexane to afford the corresponding imides.

Irreversible Inhibition of Mammalian and Insect Peptidylglycine &α-Hydroxylating Monooxygenases (PHMs), Peptide Amidating Enzymes, by N-Formyl Amides

A series of N-formyl amides were synthesized by condensation of N,N-bis(trimethylsilyl)formamide with acid chlorides (59-90percent yields), or by reaction of hydroxyglycyl peptides with 90percent hydrogen peroxide (45percent yield); a number of N-formyl amides which bear a phenyl substituent are mechanism-based irreversible inactivators of peptidylglycine α-hydroxylating monooxygenases purified from pig pituitary and from honeybee heads.