186790-84-1

Basic information

• Product Name: 1H-Pyrazole-5-carboxylic acid, 3-acetyl-4,5-dihydro-, methyl ester (9CI)
• Synonyms: 1H-Pyrazole-5-carboxylic acid, 3-acetyl-4,5-dihydro-, methyl ester (9CI)
• CAS NO: 186790-84-1
• Molecular Formula: C7H10N2O3
• Molecular Weight: 170.1659
• Product Categories: ACETYLGROUP;GLYCINESCAFFOLD
• Mol File: 186790-84-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Pyrazole-5-carboxylic acid, 3-acetyl-4,5-dihydro-, methyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazole-5-carboxylic acid, 3-acetyl-4,5-dihydro-, methyl ester (9CI)(186790-84-1)
• EPA Substance Registry System: 1H-Pyrazole-5-carboxylic acid, 3-acetyl-4,5-dihydro-, methyl ester (9CI)(186790-84-1)

Safety Data

• Hazardous Substances Data: 186790-84-1(Hazardous Substances Data)

Upstream product

• 2684-62-0 diazoacetone 
• 292638-85-8 acrylic acid methyl ester 
• 78-94-4 methyl vinyl ketone 
• 39898-83-4 1-[(triphenyl-λ⁵-phosphanylidene)hydrazinylidene]propan-2-one 

Relevant articles and documents

Reactions of diazo ketones with activated unsaturated compounds in the presence of gallium trichloride

Diazoacetone reacts with methyl acrylate in the presence of anhydrous GaCl3 to give isomeric methyl 2-acetylcyclopropanecarboxylates rather than pyrazolines obtained from diazo esters or by noncatalytic reactions. In a similar reaction, diazoacetophenone yields methyl 2-benzoylcyclopropanecarboxylates, benzoylmethyl acrylate, and benzoylmethyl 2-benzoylcyclopropanecarboxylate via partial transesterification. Addition of an equimolar amount of GaCl3 to diazoacetone in the system CH2Cl2-HCl-H2O unexpectedly produces 4,5-dimethylfuran-3(2H)-one and 1,1'-oxybis(propan-2-one).