186834-97-9

Basic information

• Product Name: 2,4-DIAMINO-6-[4-(TRIFLUOROMETHYL)PHENYL]-1,3,5-TRIAZINE
• Synonyms: 6-(4-(TRIFLUOROMETHYL)PHENYL)-1,3,5-TRIAZINE-2,4-DIAMINE;2,4-DIAMINO-6-[4-(TRIFLUOROMETHYL)PHENYL]-1,3,5-TRIAZINE;BUTTPARK 4\01-79;2,4-DIAMINO-6-(4-(TRIFLUOROMETHYL)PHENY&;1,3,5-Triazine-2,4-diaMine, 6-[4-(trifluoroMethyl)phenyl]-;2,4-Diamino-6-[(4-(trifluoromethyl)phenyl)]-1,3,5-triazine, 4-(4,6-Diamino-1,3,5-triazin-2-yl)benzotrifluoride
• CAS NO: 186834-97-9
• Molecular Formula: C10H8F3N5
• Molecular Weight: 255.2
• Product Categories: Building Blocks;Heterocyclic Building Blocks;Triazines
• Mol File: 186834-97-9.mol
• Article Data: 3

Chemical Properties

• Melting Point: 239-241 °C(lit.)
• Boiling Point: 467.8°Cat760mmHg
• Flash Point: 236.7°C
• Appearance: /
• Density: 1.479g/cm³
• Vapor Pressure: 6.31E-09mmHg at 25°C
• Refractive Index: 1.594
• CAS DataBase Reference: 2,4-DIAMINO-6-[4-(TRIFLUOROMETHYL)PHENYL]-1,3,5-TRIAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DIAMINO-6-[4-(TRIFLUOROMETHYL)PHENYL]-1,3,5-TRIAZINE(186834-97-9)
• EPA Substance Registry System: 2,4-DIAMINO-6-[4-(TRIFLUOROMETHYL)PHENYL]-1,3,5-TRIAZINE(186834-97-9)

Safety Data

• Hazard Codes: T,Xi
• Statements: 25-36/37/38
• Safety Statements: 26-36-45
• RIDADR: UN 2811 6.1/PG 2
• WGK Germany: 3
• Hazardous Substances Data: 186834-97-9(Hazardous Substances Data)

Usage

General Description

2,4-DIAMINO-6-[4-(TRIFLUOROMETHYL)PHENYL]-1,3,5-TRIAZINE, also known as DPTT, is a chemical compound commonly used in the production of rubber and other polymers. It is a white crystalline solid that is insoluble in water but soluble in organic solvents. DPTT is used as a cross-linking agent in the vulcanization process of rubber to improve its mechanical properties, such as strength and durability. It is also used as a chemical intermediate in the synthesis of other organic compounds. DPTT is considered to have low toxicity and is not known to be environmentally hazardous. However, proper handling and storage procedures should be followed to ensure safety.

InChI:InChI=1/C10H8F3N5/c11-10(12,13)6-3-1-5(2-4-6)7-16-8(14)18-9(15)17-7/h1-4H,(H4,14,15,16,17,18)

Upstream product

• 455-18-5 4-CF₃C₆H₄CN 
• 127099-85-8 N-Cyanoguanidine 

Relevant articles and documents

Synthesis, molecular docking studies, and in vitro evaluation of 1,3,5-triazine derivatives as promising antimicrobial agents

The six-membered ring heterocycle 1,3,5-triazine and its derivatives have attracted considerable attention as they have proven to be excellent bioactive herbicides, cancer agents, etc. A series of 1,3,5-triazine derivatives (3a-o) were synthesized by a single step reaction and characterized by 1H NMR, 13C NMR, and mass spectrometry analysis. Antimicrobial screening of title compounds (3a-o) was examined against five bacterial and two fungal strains. In vitro study revealed that the freshly synthesized 6-(thiazol-4-yl)-1,3,5-triazine-2,4-diamine (3o) showed good antibacterial growth inhibition against E. coli, K. pneumoniae, and A. baumannii bacterial strains, and even the fungi C. neoformans. Molecular docking studies were performed on the X-ray crystal structure of E. coli 24 kDa domain in complex with clorobiocin (PDB code: 1KZN; resolution 2.30 ?) using Surflex-Dock program of Sybyl-X software. The results obtained are very encouraging.

Model Systems for Flavoenzyme Activity. Regulation of Flavin Recognition via Modulation of Receptor Hydrogen-Bond Donor-Acceptor Properties

We have synthesized a new family of receptors for flavins based on 6-aryl-2,4-(acyldiamino)-s-triazines. In these synthetic hosts, systematic variation of the spatially remote substituents on the 6-aryl ring alters the hydrogen-bond-donating abilities of the amide functionality and the hydrogen-bond-accepting properties of the triazine N(3). This variation results in a strong modulation of the efficiency of flavin binding, with association constants for the receptor flavin complexes ranging over an 8-fold range.