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1869-45-0

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1869-45-0 Usage

General Description

Acetamide, 2,2,2-trifluoro-N-(2-mercaptoethyl)- is a chemical compound with the molecular formula C4H6F3NO. It is a trifluoromethylated derivative of acetamide with a thiol group attached to an ethyl chain. Acetamide, 2,2,2-trifluoro-N-(2-mercaptoethyl)- has been identified as a potential drug metabolite and has also been studied for its potential use in pharmaceutical research. Its chemical properties make it a valuable tool for studying the metabolism and potential therapeutic effects of related compounds. Additionally, its specific structure and functional groups make it a potentially interesting target for further chemical and biological research.

Check Digit Verification of cas no

The CAS Registry Mumber 1869-45-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,8,6 and 9 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1869-45:
(6*1)+(5*8)+(4*6)+(3*9)+(2*4)+(1*5)=110
110 % 10 = 0
So 1869-45-0 is a valid CAS Registry Number.

1869-45-0Downstream Products

1869-45-0Relevant articles and documents

A reactive oxygen species (ROS)-responsive polymer for safe, efficient, and targeted gene delivery in cancer cells

Shim, Min Suk,Xia, Younan

, p. 6926 - 6929 (2013)

Stimuli-responsive release: The high levels of reactive oxygen species (ROS) in prostate cancer cells can be exploited to trigger cancer-targeted gene delivery. A ROS-responsive thioketal-based cationic polymer was synthesized and functionalization with a cancer-targeting peptide led to selective and enhanced gene transfection in prostate cancer cells (see scheme). Copyright

Synthesis of a reactive oxygen species-responsive doxorubicin derivative

Delehanty, James B.,Das, Shivani,Goldberg, Efram,Sangtani, Ajmeeta,Knight, D. Andrew

, (2018)

A heterobifunctional reactive oxygen species (ROS)-responsive linker for directed drug assembly onto and delivery from a quantum dot (QD) nanoparticle carrier was synthesized and coupled to doxorubicin using N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride (EDC)/sulfo–NHS coupling. The doxorubicin conjugate was characterized using 1H NMR and LC-MS and subsequently reacted under conditions of ROS formation (Cu2+/H2O2) resulting in successful and rapid thioacetal oxidative cleavage, which was monitored using 1H NMR.

Thioketal connection unit, synthetic method and purpose thereof

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Paragraph 0065; 0066; 0067, (2017/01/02)

The invention discloses a thioketal connection unit, a synthetic method and a purpose thereof. The thioketal connection unit has a structure shown as a formula (I) in the specification, wherein, R=-OH or -COOH; R1 and R2 can satisfy one of the following c

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