186962-33-4Relevant articles and documents
Organocatalytic enantioselective synthesis of nitrogen-substituted dihydropyran-2-ones, a key synthetic intermediate of 1β-methylcarbapenems
Kobayashi, Shoji,Kinoshita, Tatsuhiro,Uehara, Hisatoshi,Sudo, Tomoko,Ryu, Llhyong
, p. 3934 - 3937 (2009)
Organocatalytic enantioselective cycloadditions providing nitrogen-substituted dihydropyran-2-ones were developed in two catalytic systems. The (3R,4R)-product was a versatile intermediate in the synthesis of 1β-methylcarbapenem antibiotics.