186964-36-3Relevant academic research and scientific papers
Synthesis and conformation of hexahydro-isoquino[1,2-b][3]benzazepines
Clemens, Martina,Meise, Werner,Himmel, Klaus,Jansen, Martin
, p. 447 - 457 (1997)
The synthesis of the six hexahydro-isoquino[1,2-b][3]benzazepines 13a-f is described; their conformation is investigated by NMR spectroscopic methods, X-ray analysis and dehydrogenation with mercury(II) acetate. VCH Verlagsgesellschaft mbH, 1997.
Ring expansions of tetrahydroprotoberberines and related dibenzo[c,g]azecines modulate the dopamine receptor subtype affinity and selectivity
Schulze, Maria,Siol, Oliver,Meise, Werner,Lehmann, Jochen,Enzensperger, Christoph
experimental part, p. 207 - 214 (2010/08/20)
The affinities of tetrahydroprotoberberines for dopamine receptors dramatically decrease after cleaving the central C-N bond to the analogous ten-membered dibenzo[c,g]azecines [1]. In the present work, we also synthesized eleven-membered homologues of the
