18706-27-9 Usage
Uses
Used in Organic Synthesis:
4-Bromo-6-methyl-2-(trifluoromethyl)quinoline is used as a building block in organic synthesis for the creation of complex molecules. Its unique structure allows for the formation of a variety of chemical compounds, making it a versatile component in the synthesis of new materials.
Used in Pharmaceutical Industry:
4-Bromo-6-methyl-2-(trifluoromethyl)quinoline is used as a key intermediate in the development of pharmaceuticals. Its presence in the molecular structure can contribute to the activity and efficacy of potential drug candidates, making it an important ingredient in the design and synthesis of new medications.
Used in Agrochemical Industry:
4-Bromo-6-methyl-2-(trifluoromethyl)quinoline is used as a starting material in the production of agrochemicals. Its chemical properties can be harnessed to create compounds that are effective in controlling pests and diseases in agriculture, thus playing a crucial role in the development of new agrochemical products.
Used in Scientific Research:
4-Bromo-6-methyl-2-(trifluoromethyl)quinoline is used as a research compound in various scientific studies. Its unique structure and properties make it an interesting subject for investigation, potentially leading to new discoveries and advancements in the fields of chemistry and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 18706-27-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,7,0 and 6 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 18706-27:
(7*1)+(6*8)+(5*7)+(4*0)+(3*6)+(2*2)+(1*7)=119
119 % 10 = 9
So 18706-27-9 is a valid CAS Registry Number.
18706-27-9Relevant academic research and scientific papers
Selective and efficient structural elaboration of 2-(trifluoromethyl)quinolinones
Marull, Marc,Schlosser, Manfred
, p. 1576 - 1588 (2007/10/03)
The acid-catalyzed cyclization-condensation between anilines and ethyl 4,4,4-trifluoroacetoacetate affords 1,4-dihydro-2-trifluoromethyl-4H-4-quinolinones (1), which can easily be converted into 4-bromo-2-(trifluoromethyl)quinolines. These undergo halogen/metal exchange, generating 2-trifluoromethyl-4-quinolyllithiums, when treated with butyllithium, and hydrogen/metal exchange, generating 4-bromo-2-trifluoromethyl-3-quinolyllithiums, when treated with lithium diisopropylamide. Trapping of the latter intermediates provides 3-functionalized products that may be further elaborated by electrophilic substitution of the bromine atom. A few unexpected findings resulted from these investigations, the most noteworthy being an unprecedented buttressing effect and a counterintuitive halogen reactivity. ( Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003).
