187140-05-2

Upstream product

• 111-88-6 Octanethiol 
• 187139-92-0 octyl 2,3,4,6-tetra-O-acetyl-1-thio-α-D-mannopyranoside 
• 187139-98-6 octyl 2-O-benzoyl-4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-1-thio-α-D-mannopyransoside 
• 187139-96-4 octyl 4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-1,3-diyl)-1-thio-α-D-mannopyranoside 
• 163955-47-3 octyl 1-thio-α-D-mannopyranoside 
• 83-87-4 D-Mannose pentaacetate 
• 14218-11-2 2,3,4,6-Tetra-O-benzoyl-α-D-mannopyranosyl bromide 
• 187140-02-9 octyl 2-O-benzoyl-4-O-(1-fluoro-1,1,3,3-tetraisopropyl-1,3-disiloxane-3-yl)-1-thio-α-D-mannopyranoside 

Relevant academic research and scientific papers

Synthesis of octyl O- and S-glycosides related to the GPI anchor of Trypanosoma brucei and their in vitro galactosylation by trypanosomal α-galactosyltransferases

Octyl O- and S-glycosides of mono- to tri-saccharides related to the core structure α-D-Manp-(1→2)-α-D-Manp-(1→6)-α-D-Manp of the GPI anchor of Trypanosoma brucei have been prepared via regioselective protodesilylation and glycodesilylation of octyl O- and S-glycosides of 2-O-benzoyl-4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-1,3-diyl)-α-D -mannopyranoside. The synthetic saccharides have been used as substrates for enzymatic α-galactosylation with membrane fractions of bloodstream forms of T. brucei strain 427 variants MITat 1.4, MITat 1.2, and MITat 1.5, respectively.