187219-99-4

Basic information

• Product Name: AXOMADOL,6-DIMETHYLAMINOMETHYL-1-(3-METHOXY-PHENYL)-CYCLOHEXANE-1,3-DIOL
• Synonyms: AXOMADOL,6-DIMETHYLAMINOMETHYL-1-(3-METHOXY-PHENYL)-CYCLOHEXANE-1,3-DIOL;Axomadol;Unii-9J92U4cvs0;Nicosamide
• CAS NO: 187219-99-4
• Molecular Formula: C16H25NO3
• Molecular Weight: 279.3746
• Mol File: 187219-99-4.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 431.691°C at 760 mmHg
• Flash Point: 214.879°C
• Appearance: /
• Density: 1.125g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.554
• CAS DataBase Reference: AXOMADOL,6-DIMETHYLAMINOMETHYL-1-(3-METHOXY-PHENYL)-CYCLOHEXANE-1,3-DIOL(CAS DataBase Reference)
• NIST Chemistry Reference: AXOMADOL,6-DIMETHYLAMINOMETHYL-1-(3-METHOXY-PHENYL)-CYCLOHEXANE-1,3-DIOL(187219-99-4)
• EPA Substance Registry System: AXOMADOL,6-DIMETHYLAMINOMETHYL-1-(3-METHOXY-PHENYL)-CYCLOHEXANE-1,3-DIOL(187219-99-4)

Safety Data

• Hazardous Substances Data: 187219-99-4(Hazardous Substances Data)

Usage

Uses

Treatment of pain, central analgesic.

InChI:InChI=1/C16H25NO3/c1-17(2)11-13-7-8-14(18)10-16(13,19)12-5-4-6-15(9-12)20-3/h4-6,9,13-14,18-19H,7-8,10-11H2,1-3H3/t13-,14-,16+/m1/s1

Upstream product

• 108-22-5 Isopropenyl acetate 
• 108-05-4 vinyl acetate 
• 187220-41-3 trans-4-dimethylaminomethyl-3-hydroxy-3-(3-methoxyphenyl)-cyclohexanone 
• 1174221-52-3 rac-cis-[4-dimethylaminomethyl-3-hydroxy-3-(3-methoxy-phenyl)-cyclohexanone] 
• 105-38-4 vinyl propionate 

Relevant articles and documents

Crystalline Modifications of 6-Dimethylaminomethyl-1-(3-methoxyphenyl)-cyclohexane-1,3-diol

Crystalline modifications of (1R,3R,6R)-6-dimethylaminomethyl-1-(3-methoxyphenyl)-cyclohexane-1,3-diol, (1S,3S,6S)-6-dimethylaminomethyl-1-(3-methoxyphenyl)-cyclohexane-1,3-diol and mixtures thereof, pharmaceutical compositions and medicaments comprising

Process for Producing (1RS,3RS,6RS)-6-dimethylaminomethyl-1-(3-methoxyphenyl)-cyclohexane-1,3-diol

A process for producing (1R,3R,6R)-6-dimethylaminomethyl-1-(3-methoxyphenyl)-cyclohexane-1,3-diol or (1S,3S,6S)-6-dimethylaminomethyl-1-(3-methoxyphenyl)-cyclohexane-1,3-diol or mixtures thereof.

Compositions and methods for the treatment of urinary incontinence

A pharmaceutical composition comprising an effective amount of a compound of formula I It has been surprisingly discovered that the composition of the present invention is effective for treating for the treatment of increased urinary urgency or urinary incontinence. Also disclosed are methods of treatment using said pharmaceutical compositions.