187226-50-2

Upstream product

• 4132-28-9 2,3,4,6-tetra-O-benzyl-D-mannopyranose 
• 545-06-2 trichloroacetonitrile 
• 83462-67-3 methyl 2,3,4,6-tetra-O-benzyl-D-mannopyranoside 
• 51023-63-3 methyl-α,β-D-mannopyranoside 
• 530-26-7 D-Mannose 
• 4163-65-9 per-O-acetyl-α-D-mannopyranose 
• 13992-16-0 phenyl 2,3,4,6-tetra-O-acetyl-1-thio-α-D-mannopyranoside 
• 38184-10-0 phenyl 2,3,4,6-tetra-O-benzyl-1-thio-α-D-mannopyranoside 

Downstream Products

• 1012795-71-9 N-trichloroacetyl-2,3,4,6-tetra-O-benzyl-β-D-mannopyranosylamine 
• 1134635-09-8 C₄₈H₄₈O₁₂ 
• 1134635-08-7 C₄₈H₄₈O₁₂ 
• 1134635-11-2 C₄₈H₄₈O₁₂ 
• 1134635-10-1 C₄₈H₄₈O₁₂ 
• 4132-28-9 2,3,4,6-tetra-O-benzyl-D-mannopyranose 
• 1361383-00-7 methyl [2,3,4,6-tetra-O-benzyl-β-D-mannopyranosyl]-(1->2)-3-O-benzyl-4,6-benzylidene-α-D-mannopyranoside 
• 55094-26-3 methyl 2,3,4-tri-O-benzyl-6-O-(2,3,4,6-tetra-O-benzyl-β-D-mannopyranosyl)-α-D-glucopyranoside 
• 55094-26-3 methyl 2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl-(1→6)-2,3,4-tri-O-benzyl-α-D-glucopyranoside 

Relevant academic research and scientific papers

Enhanced Spacer Length between Mannose Mimicking Shikimoyl and Quinoyl Headgroups and Hydrophobic Region of Cationic Amphiphile Increases Efficiency of Dendritic Cell Based DNA Vaccination: A Structure-Activity Investigation

In the field of dendritic cell based genetic immunization, previously we showed that liposomes of cationic amphiphiles containing mannose-mimicking shikimoyl headgroup are promising DNA vaccine carriers for dendritic cell (DC) transfection. The present structure-activity study reports on the influence of spacer length (between mannose-mimicking headgroups and quaternary nitrogen centers) in modulating the DC-transfection efficiencies. Further, we report on the anti-melanoma immune response inducing properties of the promising cationic amphiphiles in syngeneic C57BL/6J mice under prophylactic settings.

A straightforward synthesis of 1-adamantylmethyl glycosides, and their binding to cyclodextrins

A single-step synthesis of 1-adamantylmethyl α- and β-glycosides starting from commercially available peracetylated monosaccharides is reported. The α- and β-glucopyranosides 1a and 1b bind to β-cyclodextrin with association constants in the order of 10s