187266-07-5

Upstream product

• 116868-95-2 (+/-)-methyl 1,3-dimethyl-2-oxo-3-cyclohexene-1-carboxylate 
• 187266-01-9 methyl (-)-(1R)-1,3-dimethyl-2-oxocyclohex-3-ene-1-carboxylate 
• 17422-12-7 methyl 2-methyl-3-oxopentanoate 
• 187266-02-0 (1R,2S)-2-Ethynyl-2-hydroxy-1,3-dimethyl-cyclohex-3-enecarboxylic acid methyl ester 

Relevant academic research and scientific papers

Oxidative allylic rearrangement of cycloalkenols: Formal total synthesis of enantiomerically pure trisporic acid B

Enantiomerically highly enriched unsaturated β-ketoesters bearing a quaternary stereocenter can be utilized as building blocks for the synthesis of natural occurring terpenes, i. a., trisporic acid and its derivatives. An advanced building block has been

Synthesis of bicyclic homochiral dienes by allylic rearrangement of cyclohexenols - Suitable building blocks for the synthesis of nagilactones

A very short and straightforward synthesis towards highly functionalized dienes is described. The homochiral starting material, unsaturated β-oxo ester 2, can be prepared by enzyme-catalyzed saponification. The utility of the dienes has been demonstrated in a cycloaddition with N-phenyltriazolidinone as the dienophile. The Diels-Alder reaction is highly diastereoselective, yielding only one diastereomer. VCH Verlagsgesellschaft mbH, 1997.