187267-85-2Relevant academic research and scientific papers
Discovery of a potent enoyl-acyl carrier protein reductase (FabI) inhibitor suitable for antistaphylococcal agent
Kim, Yun Gyeong,Seo, Jae Hong,Kwak, Jin Hwan,Shin, Kye Jung
, p. 4481 - 4486 (2015/10/12)
We report the discovery, synthesis, and biological activities of phenoxy-4-pyrone and phenoxy-4-pyridone derivatives as novel inhibitors of enoyl-acyl carrier protein reductase (FabI). Pyridone derivatives showed better activities than pyrone derivatives
Synthesis of methyl derivatives of 4H-furo[2,3-h]quinolin-4-one and 5H-furo[3,2-g]quinolin-5-one
Rao, Vadapalli S.,Rodighiero, Paolo,Chilin, Adriana,Castellin, Andrea,Manzini, Paolo,Guiotto, Adriano
, p. 419 - 422 (2007/10/03)
Synthesis of the linear and angular furoquinolin-4-one derivatives 6 and 12 was performed, using nitrobenzofurans 3 and 9 as key intermediates. These compounds were reduced to the corresponding aminobenzofurans 4 and 10, which were condensed in two steps
