18730-39-7

Upstream product

• 622-78-6 Benzyl isothiocyanate 
• 609-85-8 2-amino-3,5-dibromobenzoic acid 
• 81190-68-3 2-amino-4,6-dibromobenzoic acid 

Downstream Products

• 77931-04-5 6,8-dibromo-3-benzyl-2-(α-methylcarboxymethylthio)-4(3H)-quinazolinone 
• 83390-42-5 2-(3-Benzyl-6,8-dibromo-4-oxo-3,4-dihydro-quinazolin-2-ylsulfanyl)-N-[5-(2-cyclohexyl-ethyl)-[1,3,4]thiadiazol-2-yl]-acetamide 
• 83390-41-4 2-(3-Benzyl-6,8-dibromo-4-oxo-3,4-dihydro-quinazolin-2-ylsulfanyl)-N-(5-cyclohexyl-[1,3,4]thiadiazol-2-yl)-acetamide 
• 24688-13-9 3-benzyl-6,8-dibromo-1H-quinazoline-2,4-dione 

Relevant academic research and scientific papers

STUDIES ON THIOQUINAZOLINONES AND SYNTHESIS OF 9-IODO-3,4-DIPHENYLTETRAZEPINOQUINAZOLIN-7(1H)-ONE

Varoius 6,8-disubstituted 3(aryl) or (alkyl)-2s-(substituted)-4(3H)-quinazolinones, 6-bromo-2-methyl-4-s-(substituted)-4(3H)-quinazolinones, bis(6,8-dibromo-3-benzyl-4-oxo-quinazolin-2-yl)disulphide, 9-iodo-3,4-diphenyltetrazepinoquinazolin-7(1H)-one and 6-iodo-2-(p-methylphenylamino)-4H-3,1-benzothiazin-4-one have been prepared.Their structures have been established on the basis of various studies.

Synthesis and evaluation of substituted quinazolone derivatives for antibacterial, antifungal, and antiacetylcholinesterase activities

The synthesis of new 6-bromo- and 6,8dibromo-2-[N-(2'-alkyl -1',3',4' -thiadiazol -5' -yl)carbamoylmethylthiol] -3- aryl/cyclohexyl-4-(3H)-quinazolones is described. The synthesized derivatives were screened for antibacterial, antifungal, and antiacetylcholinesterase activities in vitro. Most of the compounds exhibited significant biological activity. The relation between their biological activity and chemical structure was studied.