81190-68-3 Usage
Uses
Used in Pharmaceutical Synthesis:
2-Amino-4,6-Dibromobenzoic Acid is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to be incorporated into complex organic molecules, enhancing their therapeutic properties.
Used in Organic Compounds Synthesis:
In the field of organic chemistry, 2-Amino-4,6-Dibromobenzoic Acid serves as a building block for the creation of diverse organic compounds, leveraging its reactive bromine and amino functional groups.
Used in Anti-Cancer Research:
2-Amino-4,6-Dibromobenzoic Acid is utilized as a potential anti-cancer agent, with ongoing studies exploring its effects on various types of cancer. Its unique structure, including the presence of bromine atoms, may contribute to its potential as a therapeutic agent.
Used in Chemical Industry:
2-Amino-4,6-Dibromobenzoic Acid is employed in the chemical industry for various applications, such as in the development of dyes, pigments, and other specialty chemicals, due to its reactive functional groups and stability.
Check Digit Verification of cas no
The CAS Registry Mumber 81190-68-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,1,9 and 0 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 81190-68:
(7*8)+(6*1)+(5*1)+(4*9)+(3*0)+(2*6)+(1*8)=123
123 % 10 = 3
So 81190-68-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H5Br2NO2/c8-3-1-4(9)6(7(11)12)5(10)2-3/h1-2H,10H2,(H,11,12)
81190-68-3Relevant academic research and scientific papers
Design, synthesis and evaluation of new quinazolin-4-one derivatives as apoptotic enhancers and autophagy inhibitors with potent antitumor activity
ElZahabi, Heba S.A.,Nafie, Mohamed S.,Osman, Dina,Elghazawy, Nehal H.,Soliman, Dalia H.,EL-Helby, Abdelghany Ali H.,Arafa, Reem K.
, (2021/06/15)
This work presents the design and synthesis of a series of new quinazolin-4-one derivatives, based on the established effectiveness of quinazoline-based small molecules as anticancer agents. Synthesized compounds were more potent against MCF-7 than A-549
Discovery of 3-aryl-3-methyl-1H-quinoline-2,4-diones as a new class of selective 5-HT6 receptor antagonists
Seong, Churl Min,Park, Woo Kyu,Park, Chul Min,Kong, Jae Yang,Park, No Sang
, p. 738 - 743 (2008/12/23)
A 5,7-dichloro-3-phenyl-3-methyl-quinoline-2,4-dione (11a) has been identified in a random screen as a lead for 5-HT6 antagonist. During the lead optimization process, several analogs were synthesized and their biological activities were investigated. Within this series, several compounds display high binding affinity and selectivity for the 5-HT6 receptor. In particular, 3-(4-hydroxyphenyl)-3-methyl-quinoline-2,4-dione (12f) exhibits high affinity (Ki = 12.3 nM) for 5-HT6 receptor with good selectivity over other serotonin and dopamine (D1-D4) receptor subtypes. In a functional adenylyl cyclase stimulation assay, this compound exhibited considerable antagonistic activity (IC50 = 0.61 μM).
