18732-48-4

Basic information

• Product Name: 1-acetoxy-2-(5-phenyl-4,5-dihydro-isoxazol-3-yl)-benzene
• Synonyms: 1-acetoxy-2-(5-phenyl-4,5-dihydro-isoxazol-3-yl)-benzene
• CAS NO: 18732-48-4
• Molecular Weight: 281.311
• Mol File: 18732-48-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-acetoxy-2-(5-phenyl-4,5-dihydro-isoxazol-3-yl)-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-acetoxy-2-(5-phenyl-4,5-dihydro-isoxazol-3-yl)-benzene(18732-48-4)
• EPA Substance Registry System: 1-acetoxy-2-(5-phenyl-4,5-dihydro-isoxazol-3-yl)-benzene(18732-48-4)

Safety Data

• Hazardous Substances Data: 18732-48-4(Hazardous Substances Data)

Upstream product

• 4894-23-9 3,5-diphenyl-4,5-dihydro-isoxazole 
• 3240-34-4 [bis(acetoxy)iodo]benzene 

Relevant articles and documents

Palladium catalyzed C-H bond acetoxylation: Isoxazolinyl as a directing group

Pd(OAc)2-catalyzed acetoxylations of 3-aryl or 3-alkyl groups mounted on a 2-isoxazoline ring were studied. Ortho-selective C-H bond activation directed by an isoxazolinyl group was realized. 2-Isoxazoline rings without and with one or two alkyl substituents in the 5-position were effective directing groups. The substituent effect on reactivity and regioselectivity was examined. The acetoxylation was applied to the synthesis of useful intermediates.