187407-15-4

Usage

Uses

Used in Pharmaceutical Industry:
2,6-dibromo-4-iodophenol is used as a building block for the production of pharmaceuticals, contributing to the synthesis of organic molecules that form the basis of various medications. Its presence in the synthesis process is crucial for creating new and effective drugs.
Used in Agrochemical Industry:
In the agrochemical sector, 2,6-dibromo-4-iodophenol serves as a key component in the development of pesticides and other agricultural chemicals. Its role in these products helps to enhance crop protection and increase agricultural yields.
Used in Chemical Reactions as a Reagent:
2,6-dibromo-4-iodophenol is utilized as a reagent in various chemical reactions, facilitating specific transformations and syntheses that are essential for the creation of new compounds and materials.
Used as a Source of Halogen Elements in Organic Synthesis:
2,6-dibromo-4-iodophenol also serves as a source of bromine and iodine in organic synthesis, providing a convenient way to introduce these halogen atoms into organic molecules for a range of applications.
It is imperative for researchers and chemists to handle 2,6-dibromo-4-iodophenol with care due to its potential health and environmental risks, ensuring safe laboratory practices and responsible chemical management.

Upstream product

• 540-38-5 p-Iodophenol 
• 56967-16-9 4-amino-2,6-dibromo-phenol; hydrochloride 
• 608-33-3 2,6-dibromophenol 

Downstream Products

• 704909-77-3 2,6-dibromo-4-iodoanisole 
• 865722-89-0 N-[3-(2,6-dibromo-4-iodophenoxy)propyl]-2-nitrobenzenesulfonamide 
• 865722-87-8 3-(2,6-dibromo-4-iodophenoxy)-N,N-dimethyl-propylamine 
• 865722-93-6 [3-(2,6-dibromo-4-iodophenoxy)propyl]carbamic acid tert-butyl ester 
• 913172-14-2 [2-(2,6-dibromo-4-iodo-phenoxy)-ethyl]-carbamic acid tert-butyl ester 
• 913171-94-5 [2-(2,6-dibromo-4-iodo-phenoxy)-ethyl]-diisopropyl-amine 
• 913171-92-3 [2-(2,6-dibromo-4-iodo-phenoxy)-ethyl]-dimethyl-amine 
• 913171-93-4 [2-(2,6-dibromo-4-iodo-phenoxy)-ethyl]-diethyl-amine 
• 913171-95-6 1-[2-(2,6-dibromo-4-iodo-phenoxy)-ethyl]-pyrrolidine 
• 913171-98-9 1-[3-(2,6-dibromo-4-iodo-phenoxy)-propyl]-piperidine 
• 913171-97-8 4-[2-(2,6-dibromo-4-iodo-phenoxy)-ethyl]-morpholine 
• 913171-96-7 1-[2-(2,6-dibromo-4-iodo-phenoxy)-ethyl]-piperidine 
• 913171-99-0 2-[2-(2,6-dibromo-4-iodo-phenoxy)-ethyl]-1-methyl-pyrrolidine 
• 865722-88-9 (E)-methyl 3-[3,5-dibromo-4-(3-dimethylaminopropoxy)phenyl]acrylate 

Relevant academic research and scientific papers

Giant Concentric Metallosupramolecule with Aggregation-Induced Phosphorescent Emission

Fluorescent metallosupramolecules have received considerable attention due to their precisely controlled dimensions as well as the tunable photophysical and photochemical properties. However, phosphorescent analogues are still rare and limited to small structures with low-temperature phosphorescence. Herein, we report the self-assembly and photophysical studies of a giant, discrete metallosupramolecular concentric hexagon functionalized with six alkynylplatinum(II) bzimpy moieties. With a size larger than 10 nm and molecular weight higher than 26000 Da, the assembled terpyridine-based supramolecule displayed phosphorescent emission at room temperature. Moreover, the supramolecule exhibited enhanced aggregation-induced phosphorescent emission compared to the ligand by tuning the aggregation states through intermolecular interactions and significant enhancement of emission to CO2 gas.

Preparation of a psammaplysene-based library

(Chemical Equation Presented) A 28-member focused library, based on the pseudosymmetric template of the marine alkaloids psammaplysenes, was prepared from combinations of components that were, in turn, derived from 4-iodophenol.

THYROID RECEPTOR AGONISTS

The invention provides compounds of formula (I) or a pharmaceutically acceptable ester, amide, solvate or salt thereof, including a salt of such an ester or amide, and a solvate of such an ester, amide or salt. The invention also provides the use of such compounds in the treatment or prophylaxis of a condition mediated by a thyroid receptor. Formula (I), wherein R1, R2, n, Y, Y', R3, R4, W and R5 are as defined in the specification.

Total synthesis of psammaplysenes A and B, naturally occurring inhibitors of FOXO1a nuclear export

(Chemical Equation Presented) Two inhibitors of FOXO1a-mediated nuclear export, psammaplysenes A and B, have been synthesized by a flexible and efficient route. A common starting material, 4-iodophenol, was used to prepare both halves of these pseudosymme

Palladium-Catalyzed Regioselective Hydrodebromination of Dibromoindoles: Application to the Enantioselective Synthesis of Indolodioxane U86192A

A novel approach to the selective preparation of 4-bromoindoles was developed via Pd(OAc)2/rac-BINAP catalytic reactions. A variety of 4,6-dibromoindoles were transformed to 4-bromoindoles with high regioselectivity. This methodology, along wit

Highly efficient and selective procedures for the synthesis of γ-alkylidenebutenolides via palladium-catalyzed ene-yne coupling and palladium- or silver-catalyzed lactonization of (Z)-2-en-4-ynoic acids. Synthesis of rubrolides A, C, D, and E

The diacetates of rubrolides A, C, D, and E (1 a-d) were prepared in modest yields by the Pd-catalyzed cross coupling-lactonization tandem reaction of 5a or 5b with 6a or 6b using Cl2Pd(PPh3)2 and CuI as catalysts. The feasibility of converting the diacetates into rubrolides was demonstrated by the synthesis of rubrolide C by treatment of 1b with methanolic K2CO3 in THF. A detailed investigation of various parameters and conditions has indicated that formation of the corresponding six-membered lactones 7 and/or the cross coupling-lactonization-Heck substitution products 11 can be serious side reactions under non-optimized conditions and that the use of Pd(PPh3)4 rather than phosphine-free complexes, e.g., CI2Pd(PhCN)2, or complexes of low phosphine content, e.g., Cl2Pd(PPh3)2, along with CuI and NEt3 in MeCN provides satisfactory conditions for the cross coupling-lactonization tandem reaction. Thus, the diacetate of rubrolide A (1a) was prepared in 70% isolated yield. The optimized conditions reported herein appear to be generally applicable to the stereoselective and regioselective synthesis of γ-alkylidenebutenolides in a highly efficient manner.